Hasegawa Tomoko, Ooto Sotaro, Makiyama Yukiko, Hata Masayuki, Miyamoto Kazuaki, Yoshimura Nagahisa
Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Retin Cases Brief Rep. 2019;13(3):232-237. doi: 10.1097/ICB.0000000000000564.
To report cases that showed partition-like, dark areas in the cone mosaic on adaptive optics scanning laser ophthalmoscopy (AO-SLO) images in eyes with inner nuclear layer (INL) microcystic changes.
Eyes with INL microcystic changes were imaged by prototype AO-SLO.
An eye with Leber hereditary optic neuropathy, an eye with traumatic optic neuropathy, and an eye with retinitis pigmentosa that showed microcystic lesions in the INL were imaged by AO-SLO. The images revealed characteristic, dark, partition-like lesions in the cone mosaic of all the eyes in areas where microcystic changes in the INL were shown by spectral domain optical coherence tomography. The AO-SLO findings in eyes with optic neuropathy were quite similar in shape and size to those seen in eyes with retinitis pigmentosa.
We report cases that manifest dark, partition-like areas in the cone mosaic on AO-SLO images. Microcystic lesions in the INL may affect the images of the cone mosaic.
报告在内核层（INL）发生微囊肿样改变的眼中，自适应光学扫描激光检眼镜（AO-SLO）图像上视锥细胞镶嵌中显示出分隔样暗区的病例。
使用原型AO-SLO对发生INL微囊肿样改变的眼睛进行成像。
AO-SLO对1例患有Leber遗传性视神经病变的眼睛、1例患有外伤性视神经病变的眼睛以及1例患有视网膜色素变性且INL存在微囊肿样病变的眼睛进行了成像。图像显示，在所有眼睛的视锥细胞镶嵌中，在光谱域光学相干断层扫描显示INL存在微囊肿样改变的区域出现了特征性的、暗的、分隔样病变。视神经病变患者眼睛的AO-SLO表现，在形状和大小上与视网膜色素变性患者眼睛的表现非常相似。
我们报告了在AO-SLO图像上视锥细胞镶嵌中出现暗的、分隔样区域的病例。INL中的微囊肿样病变可能会影响视锥细胞镶嵌的图像。
