Baghad Bouchra, Chiheb Soumiya, Benchikhi Hakima
Université Hassan II, Hôpital Ibn Rochd, Casablanca, Maroc.
Pan Afr Med J. 2016 Dec 6;25:218. doi: 10.11604/pamj.2016.25.218.9229. eCollection 2016.
Pulsed dye laser (LCP) is currently the gold standard for Port wine stains (PWS) treatment. However, predictive clinical criteria indicating a right or poor response are not yet clear in our context. This study aims to determine the factors associated with poor/good response in Moroccan patients with PWS treated with LCP. We conducted a retrospective study of patients treated for PWS at the dermatology department at the CHU Ibn Rochd in Casablanca between January 2008 and December 2013. We collected the following clinical parameters: age, sex, location, history, parameters used, number of sessions, phototype and physician satisfaction with outcome of the bleaching therapy. A good response was defined by the achievement of 50% lesional lightening at the end of the 6th session. Patients were contacted by telephone to measure their satisfaction. These results were correlated with the clinical parameters mentioned above. We set our significance level at 0.05. Seventy-four patients were eligible The female sex represented 69% and the median age was 18 years. It occurred predominantly on the face (94%). The comparative study of good/poor responders showed that the mean age in the group of good responders was lower than that of poor responders with a significant difference (p = 0.047). The number of sessions in the group of good responders was higher (p = 0.044). The parameters were variable from one patient to another. There was no difference in the type of skin between the two groups. The best bleached location was the area V2. This study showed that patients undergoing several PWS treatment sessions at a young age had a superior therapeutic response in our context. This highlights the role of early diagnosis and short interval management to improve outcomes and minimize adverse effects.
脉冲染料激光(LCP)目前是治疗葡萄酒色斑(PWS)的金标准。然而,在我们的研究背景下,尚无明确的临床预测标准来表明治疗反应良好或不佳。本研究旨在确定在摩洛哥接受LCP治疗的PWS患者中,与治疗反应良好/不佳相关的因素。我们对2008年1月至2013年12月期间在卡萨布兰卡伊本·罗什德大学医院皮肤科接受PWS治疗的患者进行了一项回顾性研究。我们收集了以下临床参数:年龄、性别、部位、病史、使用的参数、治疗次数、皮肤类型以及医生对脱色治疗效果的满意度。治疗反应良好的定义为在第6次治疗结束时皮损减轻50%。通过电话联系患者以评估他们的满意度。将这些结果与上述临床参数进行相关性分析。我们将显著性水平设定为0.05。74例患者符合条件,其中女性占69%,中位年龄为18岁。病变主要发生在面部(94%)。对治疗反应良好/不佳的患者进行比较研究发现,治疗反应良好组的平均年龄低于治疗反应不佳组,差异有统计学意义(p = 0.047)。治疗反应良好组的治疗次数更多(p = 0.044)。不同患者之间参数各不相同。两组患者的皮肤类型无差异。脱色效果最佳的部位是V2区。本研究表明,在我们的研究背景下,年轻时接受多次PWS治疗的患者治疗反应更佳。这凸显了早期诊断和短间隔治疗对于改善治疗效果和减少不良反应的作用。