Blake Diane R, Middleman Amy B
Department of Pediatrics, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
Department of Pediatrics, University of Oklahoma Health Sciences Center, 1200 Children's Avenue, Suite 12200, Oklahoma City, OK 73104, USA.
Pediatr Clin North Am. 2017 Apr;64(2):321-329. doi: 10.1016/j.pcl.2016.11.003.
Rates of cancers attributable to human papillomavirus (HPV) are rising. A safe and extremely effective vaccine is available to prevent many of these cancers. Studies have shown that health care providers' recommendation to immunize is the most important factor in parents' decision. Parents of all adolescent boys and girls should receive a strong and unequivocal recommendation to vaccinate their child against HPV at the 11- or 12-year-old well child visit. Ideally, adolescents complete their HPV vaccine series by their 13th birthday, leading to greater immune response and protection before most adolescents are exposed to sexually transmitted HPV.
由人乳头瘤病毒（HPV）引发的癌症发病率正在上升。有一种安全且极为有效的疫苗可用于预防许多此类癌症。研究表明，医疗保健提供者的免疫接种建议是父母做出决定的最重要因素。所有青春期男孩和女孩的父母都应在孩子11或12岁进行健康体检时，收到关于为孩子接种HPV疫苗的强烈且明确的建议。理想情况下，青少年在13岁生日前完成HPV疫苗接种系列，从而在大多数青少年接触性传播HPV之前产生更强的免疫反应和保护作用。
