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[现实生活中的慢性阻塞性肺疾病。LEONPOC研究]

[Chronic obstructive pulmonary disease in real life. LEONPOC study].

作者信息

García García Silvia, Carazo Fernández Luis, Juan García Javier, Naveiro Rilo José Cesáreo

机构信息

Sección de Neumología, Complejo Asistencial Universitario de León, León, España.

Sección de Neumología, Complejo Asistencial Universitario de León, León, España.

出版信息

Aten Primaria. 2017 Dec;49(10):603-610. doi: 10.1016/j.aprim.2017.01.002. Epub 2017 Mar 11.

Abstract

OBJECTIVE

The purpose of this study was to evaluate different characteristics of COPD patients according to phenotypes and GOLD guidelines.according to GesEPOC phenotypes and GOLD 2011 ABCD guidelines and pharmacological treatment agreement.

DESIGN

Cross-sectional survey.

LOCATION

COPD patients aged 40-85 from León were randomly selected from Primary Care database, MEDORA.

PARTICIPANTS

5222 eligible COPD patients were collected from MEDORA database. We calculated a sample size of 734 patients and finally studied 577 of them.

MAIN MEASUREMENTS

Patientś clinical, functional and health related quality of life information were collected. Spirometry and postbroncodilator test were performed.

RESULTS

A total of 577 patients were included in this study. 28.7% of them did not have a spirometry recorded in their files. 123 patients had a normal or non-obstructive spirometry pattern, so they were excluded from a COPD diagnostic. With regard to treatments, there was an overprescribing of inhaled steroids in patients from GOLD A and B groups, and also in patients with the called exacerbator phenotype (GesEPOC).

CONCLUSION

Although there have been several published guidelines, management of COPD patients in real life should be improved.

摘要

目的

本研究旨在根据表型和慢性阻塞性肺疾病全球倡议(GOLD)指南,评估慢性阻塞性肺疾病(COPD)患者的不同特征。根据GesEPOC表型和GOLD 2011 ABCD指南以及药物治疗一致性。

设计

横断面调查。

地点

从莱昂年龄在40 - 85岁的COPD患者中,从初级保健数据库MEDORA中随机选取。

参与者

从MEDORA数据库收集了5222名符合条件的COPD患者。我们计算出样本量为734名患者,最终研究了其中的577名。

主要测量指标

收集患者的临床、功能和健康相关生活质量信息。进行肺量测定和支气管扩张剂后试验。

结果

本研究共纳入577名患者。其中28.7%的患者病历中没有记录肺量测定结果。123名患者的肺量测定模式正常或无阻塞,因此被排除在COPD诊断之外。关于治疗,GOLD A组和B组患者以及具有所谓加重型表型(GesEPOC)的患者存在吸入性糖皮质激素处方过量的情况。

结论

尽管已经发布了多项指南,但COPD患者在现实生活中的管理仍需改善。

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