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蛋白质分泌的新见解:TANGO1在COPII衣被周围发挥重要作用。

New insights into protein secretion: TANGO1 runs rings around the COPII coat.

作者信息

Glick Benjamin S

机构信息

Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637

出版信息

J Cell Biol. 2017 Apr 3;216(4):859-861. doi: 10.1083/jcb.201701142. Epub 2017 Mar 14.

Abstract

In this issue, Liu et al. (2017. https://doi.org/10.1083/jcb.201611088) and Raote et al. (2017. https://doi.org/10.1083/jcb.201608080) use super-resolution microscopy to visualize large COPII-coated endoplasmic reticulum (ER) export carriers. Rings of TANGO1 surround COPII, implicating TANGO1 in organizing ER exit sites and in regulating COPII coat dynamics and geometry.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ca9/5379958/20f99542c469/JCB_201701142_Fig1.jpg

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