Frühwald F, Frühwald S, Hajek P C, Schwaighofer B, Neuhold A, Wicke L
II. Med. Univ. Klinik Wien, Abt. für diagn. Radiologie.
Rofo. 1988 Jan;148(1):75-8. doi: 10.1055/s-2008-1048150.
MR tomograms of the spines of 121 patients were reviewed in order to assess the incidence and distribution of focal fat deposits in axial bone marrow. In addition, three cadaver spines were examined and cut with a band saw for macroscopic and histologic correlation. Yellow areas, histologically representing fatty replacement of hematopoetic marrow, were found macroscopically; their location was in precise correspondence to areas of focal enhanced signal intensity on T1-WI as well as T2-WI. The incidence of those focal fat spots was related to age, but not to sex; in different diseases like scoliosis, porosis and after cytostatic therapy of different malignomas they were found more frequently than in the average of the sample. Focal fatty replacement of hematopoetic bone marrow is obviously a normal phenomenon and should not be misinterpreted as a pathologic condition.
回顾了121例患者脊柱的磁共振断层扫描图像,以评估轴向骨髓中局灶性脂肪沉积的发生率和分布情况。此外,对三个尸体脊柱进行了检查,并用带锯切割以进行宏观和组织学对比。在宏观上发现了黄色区域,组织学上显示为造血骨髓的脂肪替代;其位置与T1加权成像(T1-WI)以及T2加权成像(T2-WI)上局灶性信号增强区域精确对应。这些局灶性脂肪斑的发生率与年龄有关,但与性别无关;在不同疾病如脊柱侧弯、骨质疏松症以及不同恶性肿瘤的细胞抑制治疗后,它们的出现频率高于样本平均水平。造血骨髓的局灶性脂肪替代显然是一种正常现象,不应被误解为病理状况。