Sahin Caner, Varım Ceyhun
Sakarya Akyazi State Hospiatl, ENT Clinic of Sakarya Akyazi State Hospital, Sakarya, Adapazarı, Sakarya 54000, Turkey.
Sakarya University, Medical Faculty, Internal Medicine, Adapazarı, Sakarya 54000, Turkey.
Open Access Maced J Med Sci. 2017 Mar 15;5(1):14-18. doi: 10.3889/oamjms.2017.007. Epub 2017 Jan 9.
The purpose of this study was to investigate the usefulness of the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) Mean Platelet Volume (MPV) and Red Cell Distribution Width (RDW) in the differential diagnosis and follow-up of patients with Bells Palsy.
Twenty-eight patients diagnosed with Bells Palsy and 28 control patients were included in the study. Serum samples were analysed retrospectively on the initial presentation and the seventh day of admission.
On admission, the NLR was 1.7±1.2. The mean absolute neutrophil count was 6100 ± 900/mm^3 in Bells Palsy Group. NLR was 0.9 ± 0.2. The mean absolute neutrophil count was 4400 ± 1100/mm^3 in control group. Statistically, significant changes were not observed in NLR, PLR, MPV and RDW measurements in Bells Palsy group between House-Brackman Staging.
Statistically significant changes in the neutrophil count and NLR were determined in the measurements between Bells Palsy and control group (p = 0.013, p = 0.016 respectively) on admission. A grade of the disease and NLR measurements had no statistically significant connection. RDW value was investigated for the first time in the literature for Bells Palsy patients.
本研究旨在探讨中性粒细胞与淋巴细胞比值（NLR）、血小板与淋巴细胞比值（PLR）、平均血小板体积（MPV）和红细胞分布宽度（RDW）在贝尔面瘫患者鉴别诊断及随访中的作用。
本研究纳入28例诊断为贝尔面瘫的患者和28例对照患者。回顾性分析患者初次就诊及入院第7天时的血清样本。
入院时，贝尔面瘫组的NLR为1.7±1.2，平均中性粒细胞绝对值为6100±900/mm³；对照组的NLR为0.9±0.2，平均中性粒细胞绝对值为4400±1100/mm³。在贝尔面瘫组中，根据House-Brackman分期，NLR、PLR、MPV和RDW测量值未观察到统计学上的显著变化。
入院时，贝尔面瘫组与对照组之间中性粒细胞计数和NLR的测量值存在统计学上的显著变化（分别为p = 0.013，p = 0.016）。疾病分级与NLR测量值无统计学上的显著关联。文献中首次对贝尔面瘫患者的RDW值进行了研究。
