Taheri Hakimeh, Ramin Shahrokh
Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran 14416, Iran.
Med Hypothesis Discov Innov Ophthalmol. 2016 Summer;5(2):53-57.
The aim of this study was to determine the change in the degree of astigmatism in patients treated with customized ablation photorefractive keratectomy (PRK). This is a cross-sectional study that involved 92 otherwise healthy subjects with regular and irregular astigmatism ≥ 1.25 D (mean age: 39.09 ± 7.72 years; range: 20-59 years). All study subjects were treated with customized ablation PRK using a Technolas 217p Excimer Laser System. Before and 6 months after the surgery, a refraction assessment was conducted for each subject, and the effectiveness of the surgery for correcting astigmatism was evaluated. There was a significant change in astigmatism based on the results of an automated refraction exam of -1.67 ± 1.03 D (P < 0.001), from -2.51 ± 1.45 D preoperatively to -0.87 ± 0.94 D postoperatively. There was also a significant change in subjective refraction of -2.00 ± 1.25 D (P < 0.001), from -2.46 ± 1.52 D preoperatively to -0.46 ± 0.97 D postoperatively. Therefore, our results show that customized ablation PRK is effective for correcting astigmatism ≥ 1.25 D (P < 0.001).
本研究的目的是确定接受定制消融准分子激光原位角膜磨镶术（PRK）治疗的患者散光程度的变化。这是一项横断面研究，纳入了92名其他方面健康、有规则和不规则散光且散光度数≥1.25 D的受试者（平均年龄：39.09±7.72岁；范围：20 - 59岁）。所有研究受试者均使用Technolas 217p准分子激光系统接受定制消融PRK治疗。在手术前和术后6个月，对每个受试者进行验光评估，并评估手术矫正散光的效果。根据自动验光检查结果，散光有显著变化，从术前的-2.51±1.45 D降至术后的-0.87±0.94 D，变化为-1.67±1.03 D（P<0.001）。主观验光也有显著变化，从术前的-2.46±1.52 D降至术后的-0.46±0.97 D，变化为-2.00±1.25 D（P<0.001）。因此，我们的结果表明，定制消融PRK对矫正≥1.25 D的散光有效（P<0.001）。
