Akkaya Sezen, Ozkurt Yelda Buyru
Fatih Sultan Mehmet Training and Research Hospital, Ophthalmology Department, E-5 uzeri, ust bostanci, Istanbul, Turkey.
Med Hypothesis Discov Innov Ophthalmol. 2016 Fall;5(3):74-77.
Epidemic keratoconjunctivitis (EKC), caused by certain species D human adenoviruses (Ads), is a highly contagious severe disease involving both the conjunctiva and cornea. The hallmark of this disease is the subepithelial infiltration of leukocytes, which results in corneal opacities that may persist for months or even years. In this case, of a 6-month-old infant, we report a symblepharon formation, a relatively rare outcome of EKC. In this condition, the palpebral conjunctiva adheres tightly to the bulbar conjunctiva of the eyeball. Our report is the first documentation of a symblepharon formation in an infant. Only two similar cases have been reported to date; therefore, a detailed description is of considerable interest to ophthalmologists. This is particularly interesting since a previous publication has associated symblepharon formation with an adenovirus infection, which is not usually involved in EKC. The development of a symblepharon following EKC is rare in infants. Since topical treatment cannot be applied due to severe eyelid edema, oral steroid therapy can be administered with pediatric consultation and meticulous monitoring.
流行性角结膜炎（EKC）由特定D种人腺病毒（Ads）引起，是一种极具传染性的严重疾病，累及结膜和角膜。该病的特征是白细胞在角膜上皮下浸润，导致角膜混浊，可能持续数月甚至数年。在本病例中，我们报告了一名6个月大婴儿出现睑球粘连，这是EKC相对罕见的结果。在这种情况下，睑结膜紧密粘连于眼球的球结膜。我们的报告是婴儿睑球粘连形成的首次记录。迄今为止，仅报告了两例类似病例；因此，详细描述对眼科医生具有相当大的吸引力。这尤其有趣，因为先前的一篇出版物将睑球粘连形成与腺病毒感染相关联，而腺病毒感染通常不涉及EKC。EKC后发生睑球粘连在婴儿中很罕见。由于严重眼睑水肿无法进行局部治疗，可在儿科会诊和精心监测下给予口服类固醇治疗。
