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本文引用的文献

1
The nasal methylome and childhood atopic asthma.鼻腔甲基化组与儿童特应性哮喘
J Allergy Clin Immunol. 2017 May;139(5):1478-1488. doi: 10.1016/j.jaci.2016.07.036. Epub 2016 Oct 13.
2
Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways.全基因组甲基化研究确定了哮喘气道中白细胞介素-13诱导的表观遗传特征。
Am J Respir Crit Care Med. 2016 Feb 15;193(4):376-85. doi: 10.1164/rccm.201506-1243OC.
3
DNA methylation and childhood asthma in the inner city.城市中心区的DNA甲基化与儿童哮喘
J Allergy Clin Immunol. 2015 Jul;136(1):69-80. doi: 10.1016/j.jaci.2015.01.025. Epub 2015 Mar 11.
4
An epigenome-wide association study of total serum immunoglobulin E concentration.一项关于血清总免疫球蛋白E浓度的全表观基因组关联研究。
Nature. 2015 Apr 30;520(7549):670-674. doi: 10.1038/nature14125. Epub 2015 Feb 18.
5
Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease.通过鼻腔转录组学剖析儿童哮喘，可区分疾病的亚表型。
J Allergy Clin Immunol. 2014 Mar;133(3):670-8.e12. doi: 10.1016/j.jaci.2013.11.025. Epub 2014 Feb 2.
6
Genome-wide association studies in asthma; perhaps, the end of the beginning.哮喘的全基因组关联研究；或许，这只是开始的结束。
Curr Opin Allergy Clin Immunol. 2013 Oct;13(5):463-9. doi: 10.1097/ACI.0b013e328364ea5f.
7
Estimates of asthma heritability in a large twin sample.大规模双胞胎样本中哮喘遗传度的估计。
Clin Exp Allergy. 2010 Jul;40(7):1054-61. doi: 10.1111/j.1365-2222.2010.03525.x. Epub 2010 May 26.
8
T-helper type 2-driven inflammation defines major subphenotypes of asthma.2型辅助性T细胞驱动的炎症反应定义了哮喘的主要亚表型。
Am J Respir Crit Care Med. 2009 Sep 1;180(5):388-95. doi: 10.1164/rccm.200903-0392OC. Epub 2009 May 29.
9
Environmental epigenomics and disease susceptibility.环境表观基因组学与疾病易感性
Nat Rev Genet. 2007 Apr;8(4):253-62. doi: 10.1038/nrg2045.
10
DNA methylation changes at human Th2 cytokine genes coincide with DNase I hypersensitive site formation during CD4(+) T cell differentiation.人类Th2细胞因子基因的DNA甲基化变化与CD4(+) T细胞分化过程中DNase I超敏位点的形成相一致。
J Immunol. 2002 Aug 15;169(4):1893-903. doi: 10.4049/jimmunol.169.4.1893.

The Nasal Methylome: A Key to Understanding Allergic Asthma.

作者信息

Yang Ivana V, Richards Adam, Davidson Elizabeth J, Stevens Allen D, Kolakowski Christena A, Martin Richard J, Schwartz David A

机构信息

1 University of Colorado School of Medicine Aurora, Colorado and.

2 National Jewish Health Denver, Colorado.

出版信息

Am J Respir Crit Care Med. 2017 Mar 15;195(6):829-831. doi: 10.1164/rccm.201608-1558LE.

DOI:10.1164/rccm.201608-1558LE
PMID:28294656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5363969/
Abstract
摘要