The Nasal Methylome: A Key to Understanding Allergic Asthma.
作者信息
Yang Ivana V, Richards Adam, Davidson Elizabeth J, Stevens Allen D, Kolakowski Christena A, Martin Richard J, Schwartz David A
机构信息
1 University of Colorado School of Medicine Aurora, Colorado and.
2 National Jewish Health Denver, Colorado.
出版信息
Am J Respir Crit Care Med. 2017 Mar 15;195(6):829-831. doi: 10.1164/rccm.201608-1558LE.
Abstract
摘要
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本文引用的文献
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The nasal methylome and childhood atopic asthma.鼻腔甲基化组与儿童特应性哮喘
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Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways.全基因组甲基化研究确定了哮喘气道中白细胞介素-13诱导的表观遗传特征。
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DNA methylation and childhood asthma in the inner city.城市中心区的DNA甲基化与儿童哮喘
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Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease.通过鼻腔转录组学剖析儿童哮喘，可区分疾病的亚表型。
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Genome-wide association studies in asthma; perhaps, the end of the beginning.哮喘的全基因组关联研究；或许，这只是开始的结束。
Curr Opin Allergy Clin Immunol. 2013 Oct;13(5):463-9. doi: 10.1097/ACI.0b013e328364ea5f.
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Estimates of asthma heritability in a large twin sample.大规模双胞胎样本中哮喘遗传度的估计。
Clin Exp Allergy. 2010 Jul;40(7):1054-61. doi: 10.1111/j.1365-2222.2010.03525.x. Epub 2010 May 26.
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T-helper type 2-driven inflammation defines major subphenotypes of asthma.2型辅助性T细胞驱动的炎症反应定义了哮喘的主要亚表型。
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Environmental epigenomics and disease susceptibility.环境表观基因组学与疾病易感性
Nat Rev Genet. 2007 Apr;8(4):253-62. doi: 10.1038/nrg2045.
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DNA methylation changes at human Th2 cytokine genes coincide with DNase I hypersensitive site formation during CD4(+) T cell differentiation.人类Th2细胞因子基因的DNA甲基化变化与CD4(+) T细胞分化过程中DNase I超敏位点的形成相一致。
J Immunol. 2002 Aug 15;169(4):1893-903. doi: 10.4049/jimmunol.169.4.1893.
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