• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

下颌第三磨牙拔除术后经皮和口内低强度激光治疗的效果:一项随机单盲、安慰剂对照双中心研究。

The Effects of Transcutaneous and Intraoral Low-Level Laser Therapy After Extraction of Lower Third Molars: A Randomized Single Blind, Placebo Controlled Dual-Center Study.

作者信息

Kahraman Sevil Altundag, Cetiner Sedat, Strauss Robert A

机构信息

1 Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gazi University , Ankara, Türkiye .

2 Department of Oral and Maxillofacial Surgery, Virginia Commonwealth University Medical Center , Richmond, Virginia.

出版信息

Photomed Laser Surg. 2017 Aug;35(8):401-407. doi: 10.1089/pho.2016.4252. Epub 2017 Mar 14.

DOI:10.1089/pho.2016.4252
PMID:28294694
Abstract

OBJECTIVE AND BACKGROUND

The surgical removal of impacted third molars is one of the most common procedures performed by oral and maxillofacial surgeons. The purpose of this study is to determine whether either transcutaneous or intraoral low-level laser therapy (LLLT) reduces postoperative pain and assists in the healing of mandibular third molar extraction.

MATERIALS AND METHODS

This randomized, placebo controlled, single-blind, split-mouth design study was conducted on 60 patients with full bony impacted similar position mandibular third molars bilaterally. The patients were divided into two groups of 30 each: transcutaneous LLLT and intraoral LLLT and the other side of each group treated with nonactive laser (60 teeth). The laser treatment consisted of administering laser energy immediately before and after the extraction procedure with gallium aluminum arsenide (GaAlAs) 830 nm diode lasers. Postoperative pain and healing of the sockets were compared in transcutaneous and intraoral group with placebo for 1 week following the extraction. Descriptive and bivariate statistics was computed, and the p-value was set at 0.05.

RESULTS

Intraoral LLLT application resulted in a statistically significant reduction of postoperative pain in comparison with transcutaneous laser group and placebo. The unhealed socket numbers were compared in two groups at seventh day and no differences were observed.

CONCLUSIONS

The results of this study suggest that single-session intraoral LLLT is more effective than extraoral application for reducing postoperative pain. It was postulated that the differences between skin and mucosa could have effect on the results. Although intraoral use would allow closer application to the surgical site, the size of some laser devices precludes their use intraorally.

摘要

目的与背景

拔除阻生第三磨牙是口腔颌面外科医生最常开展的手术之一。本研究旨在确定经皮或口内低强度激光治疗(LLLT)是否能减轻术后疼痛并促进下颌第三磨牙拔除后的愈合。

材料与方法

本研究采用随机、安慰剂对照、单盲、双侧口内对照设计,对60例双侧下颌第三磨牙完全骨阻生且位置相似的患者进行研究。患者被分为两组,每组30例:经皮LLLT组和口内LLLT组,每组的另一侧用非活性激光治疗(共60颗牙)。激光治疗包括在拔牙手术前后立即使用波长830 nm的砷化镓铝(GaAlAs)二极管激光给予激光能量。拔牙后1周,比较经皮组和口内组与安慰剂组的术后疼痛及牙槽窝愈合情况。计算描述性和双变量统计量,p值设定为0.05。

结果

与经皮激光组和安慰剂组相比,口内应用LLLT术后疼痛有统计学显著减轻。比较两组术后第7天未愈合牙槽窝数量,未观察到差异。

结论

本研究结果表明,单次口内LLLT在减轻术后疼痛方面比口外应用更有效。据推测,皮肤和黏膜的差异可能对结果产生影响。尽管口内使用可使激光更接近手术部位,但一些激光设备的尺寸使其无法在口内使用。

相似文献

1
The Effects of Transcutaneous and Intraoral Low-Level Laser Therapy After Extraction of Lower Third Molars: A Randomized Single Blind, Placebo Controlled Dual-Center Study.下颌第三磨牙拔除术后经皮和口内低强度激光治疗的效果:一项随机单盲、安慰剂对照双中心研究。
Photomed Laser Surg. 2017 Aug;35(8):401-407. doi: 10.1089/pho.2016.4252. Epub 2017 Mar 14.
2
Placebo-controlled randomized clinical trial of the effect two different low-level laser therapies (LLLT)--intraoral and extraoral--on trismus and facial swelling following surgical extraction of the lower third molar.安慰剂对照随机临床试验研究两种不同低水平激光疗法(LLLT)——口腔内和口腔外——对下颌第三磨牙拔出术后牙关紧闭和面部肿胀的影响。
Lasers Med Sci. 2010 Sep;25(5):641-5. doi: 10.1007/s10103-009-0684-1. Epub 2009 May 31.
3
Is Low-Level Laser Therapy Effective in the Management of Pain and Swelling After Mandibular Third Molar Surgery?低强度激光疗法对下颌第三磨牙手术后疼痛和肿胀的管理有效吗?
J Oral Maxillofac Surg. 2016 Jul;74(7):1322.e1-8. doi: 10.1016/j.joms.2016.02.030. Epub 2016 Mar 12.
4
Efficacy of a single dose of low-level laser therapy in reducing pain, swelling, and trismus following third molar extraction surgery.单次低强度激光治疗对减轻第三磨牙拔除术后疼痛、肿胀和牙关紧闭的疗效。
Int J Oral Maxillofac Surg. 2016 Mar;45(3):392-8. doi: 10.1016/j.ijom.2015.10.023. Epub 2015 Dec 12.
5
Therapeutic effects of low-level laser therapy after premolar extraction in adolescents: a randomized double-blind clinical trial.青少年前磨牙拔除后低强度激光治疗的疗效:一项随机双盲临床试验。
Photomed Laser Surg. 2012 Sep;30(9):559-64. doi: 10.1089/pho.2012.3243. Epub 2012 Aug 7.
6
Evaluation of the effects of the low-level laser therapy on swelling, pain, and trismus after removal of impacted lower third molar.评估低强度激光治疗对拔除下颌阻生第三磨牙后肿胀、疼痛和牙关紧闭的影响。
Head Face Med. 2016 Jul 26;12(1):25. doi: 10.1186/s13005-016-0121-1.
7
Three-dimensional evaluation of the effect of low-level laser therapy on facial swelling after lower third molar surgery: A randomized, placebo-controlled study.低强度激光疗法对下颌第三磨牙拔除术后面部肿胀影响的三维评估:一项随机、安慰剂对照研究。
Niger J Clin Pract. 2018 Sep;21(9):1107-1113. doi: 10.4103/njcp.njcp_38_18.
8
Effect of low-level laser therapy on the post-surgical inflammatory process after third molar removal: study protocol for a double-blind randomized controlled trial.低强度激光疗法对第三磨牙拔除术后炎症过程的影响:一项双盲随机对照试验的研究方案
Trials. 2013 Nov 6;14:373. doi: 10.1186/1745-6215-14-373.
9
Low-Level Laser Therapy After Wisdom Teeth Surgery: Evaluation of Immunologic Markers (Secretory Immunoglobulin A and Lysozyme Levels) and Thermographic Examination: Placebo Controlled Study.智齿拔除术后低强度激光疗法:免疫标志物(分泌型免疫球蛋白A和溶菌酶水平)评估及热成像检查:安慰剂对照研究
Photomed Laser Surg. 2017 Nov;35(11):616-621. doi: 10.1089/pho.2016.4214. Epub 2017 May 16.
10
Effectiveness of Low-Level Laser Therapy with a 915 Nm Wavelength Diode Laser on the Healing of Intraoral Mucosal Wound: An Animal Study and a Double-Blind Randomized Clinical Trial.低强度激光疗法(波长 915nm 半导体激光)对口腔黏膜伤口愈合的疗效:动物研究和双盲随机临床试验。
Medicina (Kaunas). 2019 Jul 24;55(8):405. doi: 10.3390/medicina55080405.

引用本文的文献

1
Effects of Photobiomodulation Therapy (PBMT) in the Management of Postoperative Pain After Third Lower Molar Extraction: A Narrative Review.光生物调节疗法(PBMT)在第三磨牙拔除术后疼痛管理中的作用:一项叙述性综述
J Clin Med. 2025 Jul 23;14(15):5210. doi: 10.3390/jcm14155210.
2
Comparison of the effects of antibiotic therapy and photobiomodulation with red and infrared lasers on the healing of postextraction sockets of third molars: A randomised controlled trial.抗生素治疗与红、红外激光光生物调节对第三磨牙拔牙窝愈合影响的比较:一项随机对照试验。
Lasers Med Sci. 2025 Apr 17;40(1):196. doi: 10.1007/s10103-025-04445-4.
3
Cost-Effectiveness Analysis of Photobiomodulation After Third Molar Extraction for Pain Control.
第三磨牙拔除术后用于疼痛控制的光生物调节疗法的成本效益分析。
Int J Environ Res Public Health. 2025 Jan 25;22(2):159. doi: 10.3390/ijerph22020159.
4
Evaluation of patient comfort and satisfaction after the surgical removal of mandibular impacted molars using a piezo-electric technique: A randomized double-blind clinical trial.使用压电技术拔除下颌阻生磨牙后患者舒适度和满意度的评估:一项随机双盲临床试验。
J Oral Biol Craniofac Res. 2025 Jan-Feb;15(1):108-112. doi: 10.1016/j.jobcr.2024.12.009. Epub 2024 Dec 24.
5
Complementary and alternative therapies for managing postoperative pain after lower third molar surgery: a systematic review and network meta-analysis.补充和替代疗法用于管理下颌第三磨牙手术后的术后疼痛:系统评价和网络荟萃分析。
Clin Oral Investig. 2024 Mar 28;28(4):231. doi: 10.1007/s00784-024-05625-2.
6
Green tea and hyaluronic acid gel enhance fibroblast activation and improves the gingival healing post-third molar extraction.绿茶和透明质酸凝胶可增强成纤维细胞的激活作用,并改善第三磨牙拔除后的牙龈愈合。
Sci Rep. 2024 Mar 26;14(1):7124. doi: 10.1038/s41598-024-57821-5.
7
Clinical and thermographic evaluation after lower third molar extractions and the application of different photobiomodulation protocols: double-blind randomised clinical trial.第三磨牙低位阻生拔除术后的临床和热像评估及不同光生物调节方案的应用:双盲随机临床试验。
Clin Oral Investig. 2024 Mar 8;28(3):203. doi: 10.1007/s00784-024-05594-6.
8
Effectiveness of low power laser in reducing postoperative signs and symptoms after third molar surgery: a triple-blind clinical trial.低强度激光减少第三磨牙手术后术后症状和体征的效果:一项三盲临床试验。
Braz Dent J. 2023 Jul-Aug;34(4):158-168. doi: 10.1590/0103-6440202305413.
9
Low-level laser and management of common complications after the mandibular third molar surgery: A double-blind randomized clinical trial.低强度激光与下颌第三磨牙手术后常见并发症的处理:一项双盲随机临床试验。
Dent Res J (Isfahan). 2023 Jan 18;20:14. eCollection 2023.
10
Effect of preemptive photobiomodulation associated with nimesulide on the postsurgical outcomes, oxidative stress, and quality of life after third molar surgery: a randomized, split-mouth, controlled clinical trial.预先性光生物调节联合尼美舒利对第三磨牙术后手术结局、氧化应激和生活质量的影响:一项随机、分侧、对照的临床试验。
Clin Oral Investig. 2022 Dec;26(12):6941-6960. doi: 10.1007/s00784-022-04649-w. Epub 2022 Aug 11.