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青少年前磨牙拔除后低强度激光治疗的疗效:一项随机双盲临床试验。

Therapeutic effects of low-level laser therapy after premolar extraction in adolescents: a randomized double-blind clinical trial.

作者信息

Paschoal Marco Aurélio Benini, Santos-Pinto Lourdes

机构信息

Department of Pediatric Dentistry, Araraquara Dental School, UNESP-University Estadual Paulista, São Paulo, Brazil.

出版信息

Photomed Laser Surg. 2012 Sep;30(9):559-64. doi: 10.1089/pho.2012.3243. Epub 2012 Aug 7.

Abstract

OBJECTIVE

The purpose of this study was to evaluate the effect of low-level laser therapy (LLLT) on wound healing process and pain levels after premolar extraction in adolescents.

BACKGROUND DATA

The advantage of using LLLT in oral surgeries is the reduction of inflammation and postoperative discomfort; however, the optimal dosing parameters and treatment effects in surgical procedures are inconclusive.

METHODS

A double-blind, randomized, controlled clinical trial was conducted with 14 patients who were to undergo surgical removal of premolars. Patients were randomly allocated to the LLLT (test) group and placebo (control) group. Patients in the test group received 5.1 J (60 J/cm(2)) of energy density of a gallium-aluminum-arsenide (GaAlAs) diode laser (wavelength, 830 nm; output power, 0.1 W) at three different points intraorally, 1 cm from the target tissue immediately and at 48 and 72 h after the surgical procedure. For patients in the placebo group, the laser device was applied to the same points without activating the hand piece. The wound healing process was evaluated by an independent examiner by visual inspection with the support of digital photographs at baseline and 2, 7, and 15 days postoperatively. Patients recorded the degree of pain using the visual analogue scale (VAS).

RESULTS

Compared with the placebo group, the test group showed a lower intensity of pain, but this difference was not statistically significant at any time point. The wound healing process was similar in both groups.

CONCLUSIONS

Within the limitations of this study, the LLLT parameters used neither increased the wound healing process nor significantly decreased pain intensity after premolar extraction in adolescents.

摘要

目的

本研究旨在评估低强度激光疗法(LLLT)对青少年前磨牙拔除术后伤口愈合过程及疼痛程度的影响。

背景资料

在口腔外科手术中使用LLLT的优势在于减轻炎症和术后不适;然而,手术操作中的最佳剂量参数及治疗效果尚无定论。

方法

对14例拟行前磨牙拔除术的患者进行了一项双盲、随机、对照临床试验。患者被随机分为LLLT(试验)组和安慰剂(对照)组。试验组患者在口腔内三个不同点接受波长为830nm、输出功率为0.1W的砷化镓铝(GaAlAs)二极管激光,能量密度为5.1J(60J/cm²),分别在手术即刻、术后48小时和72小时距目标组织1cm处照射。安慰剂组患者则在相同部位使用激光设备,但不启动手柄。由一名独立检查者在基线及术后2天、7天和15天通过目视检查并借助数码照片评估伤口愈合过程。患者使用视觉模拟量表(VAS)记录疼痛程度。

结果

与安慰剂组相比,试验组疼痛强度较低,但在任何时间点,这种差异均无统计学意义。两组伤口愈合过程相似。

结论

在本研究的局限性范围内,所使用的LLLT参数既未加快青少年前磨牙拔除术后的伤口愈合过程,也未显著降低疼痛强度。

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