Varon David E, Freitas Gil, Goel Neha, Wall Jennifer, Bharadia Deepak, Sisk Erin, Vacanti Joshua C, Pomahac Bohdan, Sinha Indranil, Patel Vihas M
From the *Division of Plastic Surgery, Brigham and Women's Hospital, Boston, Massachusetts; †Department of Surgery, University of Massachusetts Medical School, Worcester; ‡Department of Surgery, Columbia University Medical Center, Milstein Hospital, New York, New York; §Department of Physician Assistant Studies, George Washington University, Washington; ‖Division of Plastic and Reconstructive Surgery, University of California, San Francisco; ¶Department of Nutrition, Brigham and Women's Hospital, Boston, Massachusetts; #Department of Anesthesia, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and **Department of Surgery, Long Island Jewish Medical Center, New Hyde Park, New York.
J Burn Care Res. 2017 Sep/Oct;38(5):299-303. doi: 10.1097/BCR.0000000000000514.
Enteral nutrition support is a critical component of modern burn care for severely burned patients. However, tube feeds are frequently withheld during the perioperative period because of aspiration concerns. As a result, patients requiring multiple operative procedures risk accumulating significant protein-calorie deficits. The objective of this study was to describe our American Burn Association-certified burn center's experience implementing an intraoperative feeding protocol in severely burned patients defined as a cutaneous burn ≥20% TBSA. A retrospective review of patients with major thermal injuries (2008-2013). Thirty-three patients with an average of seven operating room trips (range, 2-21 trips) were evaluated. Seventeen patients received intraoperative enteral feeds (protocol group) and 16 patients did not (standard group). Feeding was performed using an enteral feeding tube placed postpylorically and was continued intraoperatively, regardless of operative positioning. There was no statistically significant difference in mortality between the groups (P = .62). No intraoperative aspiration or regurgitation events were recorded. The protocol group received significantly more calculated protein and caloric requirements, 98.06 and 98.4%, respectively, compared with 70.6 and 73.2% in the standard group (P < .001). Time to goal tube feed infusion rate was achieved on average 3 days sooner in the protocol group compared with the standard group (3.35 vs 6.18 days, P = .008). Early initiation and continuation of enteral feeds in severely burned patients led to higher percentages received of prescribed goal protein and caloric needs without increased rates of aspiration, regurgitation, or mortality.
肠内营养支持是重度烧伤患者现代烧伤治疗的关键组成部分。然而,由于担心误吸,围手术期常停用管饲。因此,需要进行多次手术的患者有累积显著蛋白质 - 热量不足的风险。本研究的目的是描述我们美国烧伤协会认证的烧伤中心在定义为皮肤烧伤面积≥20% 体表面积的重度烧伤患者中实施术中喂养方案的经验。对重大热损伤患者(2008 - 2013年)进行回顾性研究。评估了33例平均进行7次手术室手术(范围为2 - 21次)的患者。17例患者接受术中肠内喂养(方案组),16例患者未接受(标准组)。使用置于幽门后放置的肠内喂养管进行喂养,术中持续进行,无论手术体位如何。两组之间的死亡率无统计学显著差异(P = 0.62)。未记录到术中误吸或反流事件。与标准组的70.6%和73.2%相比,方案组分别显著更多地达到了计算出的蛋白质和热量需求,分别为98.06%和98.4%(P < 0.001)。与标准组相比,方案组平均提前3天达到目标管饲输注速率(3.35天对6.18天,P = 0.008)。重度烧伤患者早期开始并持续肠内喂养可使规定目标蛋白质和热量需求的接受比例更高,而不会增加误吸、反流或死亡率。