Manimaran K, Chandramohan M, Kannan R, Sankaranarayanan S, Ravi V R, Sharma Rohini
KSR Institute of Dental Science and Research, Department of Oromaxillofacial Surgery, Tiruchengode, TN, India.
Mother Cell Regenerative Centre, Trichy, TN, India.
J Stem Cells. 2016;11(3):121-124.
Ameloblastoma is a histologically benign odontogenic tumour and has a tendency of locally aggressive behaviour. This is second most prevalent odontogenic tumour and most common in the molar-ramus-angle region and surgical resection is only treatment option. In this article, we propose an innovative approach to deal with these cases by using alloplastic graft with cord stem cells. Over 2.5 years follow-up, we could demonstrate bone regeneration using this technique with no recurrence. To the best of our knowledge, this is the first report of successful regeneration of part of ramus and body of mandible using allogeneic cord stem cells in cases of Ameloblastoma.
成釉细胞瘤是一种组织学上良性的牙源性肿瘤，具有局部侵袭性行为的倾向。它是第二常见的牙源性肿瘤，最常见于磨牙-升支-角区，手术切除是唯一的治疗选择。在本文中，我们提出了一种创新方法，通过使用带脐带干细胞的异体移植物来处理这些病例。经过超过2.5年的随访，我们能够证明使用该技术可实现骨再生且无复发。据我们所知，这是首例在成釉细胞瘤病例中使用异体脐带干细胞成功再生下颌骨升支和体部部分的报告。
