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一名丛状成釉细胞瘤患者采用自体人骨髓干细胞和自体骨移植进行下颌骨重建。

Mandibular reconstruction with autologous human bone marrow stem cells and autogenous bone graft in a patient with plexiform ameloblastoma.

作者信息

Kim Bong Chul, Yoon Jung-Hoon, Choi Boyoung, Lee Jun

机构信息

Department of Oral and Maxillofacial Surgery, Daejeon Dental Hospital, College of Dentistry, Wonkwang University, Daejeon, Korea.

出版信息

J Craniofac Surg. 2013 Jul;24(4):e409-11. doi: 10.1097/SCS.0b013e318292c91d.

DOI:10.1097/SCS.0b013e318292c91d
PMID:23851884
Abstract

Ameloblastoma is a histologically benign tumor, but it shows a tendency of locally aggressive behavior. To our knowledge, this is the first report of a successful reconstruction performed for treating a mandibular defect by using autologous human bone marrow mesenchymal stem cells in a patient with plexiform ameloblastoma. In this article, we report the result of the mandibular reconstruction with autologous human bone marrow mesenchymal stem cells and autogenous bone graft, followed by the placement of osteointegrated dental implant and prosthodontic treatment in a patient with plexiform ameloblastoma.

摘要

成釉细胞瘤是一种组织学上的良性肿瘤,但具有局部侵袭性行为的倾向。据我们所知,这是首例使用自体人骨髓间充质干细胞治疗丛状成釉细胞瘤患者下颌骨缺损并成功重建的报告。在本文中,我们报告了一名丛状成釉细胞瘤患者采用自体人骨髓间充质干细胞和自体骨移植进行下颌骨重建,随后植入骨整合牙种植体并进行口腔修复治疗的结果。

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