Hajrasouliha Amir R, Garcia-Gonzales Jose M, Shapiro Michael J, Yoon Hawke, Blair Michael P
Ophthalmic Surg Lasers Imaging Retina. 2017 Mar 1;48(3):255-259. doi: 10.3928/23258160-20170301-10.
Although intravitreal injection of anti-vascular endothelial growth factor agents (IVA) can induce rapid regression of retinopathy of prematurity (ROP), late reactivation of the ROP can occur in the form of tractional retinal detachment (TRD) from contracted recurrent extraretinal fibrovascular proliferation. The authors report a case of bilateral TRD for recurrent ROP in a 3-year-old, which is the latest-reported reactivation to date. The authors propose that persistent avascular retina in eyes that have undergone IVA for ROP receive laser ablation to prevent late recurrences. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:255-259.].
尽管玻璃体内注射抗血管内皮生长因子药物（IVA）可促使早产儿视网膜病变（ROP）迅速消退，但ROP后期可能会因复发性视网膜外纤维血管增殖收缩导致牵拉性视网膜脱离（TRD）而再次激活。作者报告了一例3岁儿童双侧复发性ROP导致TRD的病例，这是迄今为止报告的最晚再次激活病例。作者建议，对于接受过IVA治疗ROP的眼睛，持续存在的无血管视网膜应接受激光消融，以防止后期复发。[《眼科手术、激光与影像学杂志》。2017年；48:255 - 259。]
