Ahmad Rani, Ajlan Amr M, Eskander Ayman A, Alhazmi Turki A, Khashoggi Khalid, Wazzan Mohammad A, Abduljabbar Ahmed H
Department of Radiology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.
Insights Imaging. 2021 Aug 18;12(1):118. doi: 10.1186/s13244-021-01064-9.
Crohn's disease (CD) is a condition that can occur in any part of the gastrointestinal tract, although usually forms in the colon and terminal ileum. Magnetic resonance imaging (MRI) has become a beneficial modality in the evaluation of small bowel activity. This study reports on a systematic review and meta-analysis of magnetic resonance enterography for the prediction of CD activity and evaluation of outcomes and possible complications.
Following the PRISMA guidelines, a total of 25 low-risk studies on established CD were selected, based on a QUADAS-II score of ≥ 9.
A sensitivity of 90% was revealed in a pooled analysis of the 19 studies, with heterogeneity of χ = 81.83 and I of 80.3%. Also, a specificity of 89% was calculated, with heterogeneity of χ = 65.12 and I of 70.0%.
It was concluded that MRI provides an effective alternative to CT enterography in the detection of small bowel activity in CD patients under supervision of radiologist for assessment of disease activity and its complications. Its advantages include the avoidance of radiation exposure and good diagnostic accuracy.
克罗恩病（CD）可发生于胃肠道的任何部位，不过通常在结肠和回肠末端发病。磁共振成像（MRI）已成为评估小肠活动的一种有益方式。本研究报告了一项关于磁共振小肠造影预测CD活动及评估结局和可能并发症的系统评价和荟萃分析。
按照PRISMA指南，基于QUADAS-II评分≥9，共选取了25项关于确诊CD的低风险研究。
对19项研究的汇总分析显示敏感性为90%，异质性χ=81.83，I为80.3%。此外，计算出特异性为89%，异质性χ=65.12，I为70.0%。
得出的结论是，在放射科医生监督下，MRI在检测CD患者小肠活动以评估疾病活动及其并发症方面，是CT小肠造影的一种有效替代方法。其优点包括避免辐射暴露和良好的诊断准确性。
