• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

语义健康知识图谱:异构医学知识与服务的语义集成

Semantic Health Knowledge Graph: Semantic Integration of Heterogeneous Medical Knowledge and Services.

作者信息

Shi Longxiang, Li Shijian, Yang Xiaoran, Qi Jiaheng, Pan Gang, Zhou Binbin

机构信息

College of Computer Science and Technology, Zhejiang University, Hangzhou 310027, China.

出版信息

Biomed Res Int. 2017;2017:2858423. doi: 10.1155/2017/2858423. Epub 2017 Feb 12.

DOI:10.1155/2017/2858423
PMID:28299322
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5337312/
Abstract

With the explosion of healthcare information, there has been a tremendous amount of heterogeneous textual medical knowledge (TMK), which plays an essential role in healthcare information systems. Existing works for integrating and utilizing the TMK mainly focus on straightforward connections establishment and pay less attention to make computers interpret and retrieve knowledge correctly and quickly. In this paper, we explore a novel model to organize and integrate the TMK into conceptual graphs. We then employ a framework to automatically retrieve knowledge in knowledge graphs with a high precision. In order to perform reasonable inference on knowledge graphs, we propose a contextual inference pruning algorithm to achieve efficient chain inference. Our algorithm achieves a better inference result with precision and recall of 92% and 96%, respectively, which can avoid most of the meaningless inferences. In addition, we implement two prototypes and provide services, and the results show our approach is practical and effective.

摘要

随着医疗保健信息的爆炸式增长,出现了大量异构文本医学知识(TMK),其在医疗保健信息系统中发挥着至关重要的作用。现有的整合和利用TMK的工作主要集中在建立直接的联系,而较少关注使计算机正确、快速地解释和检索知识。在本文中,我们探索了一种新颖的模型,将TMK组织并整合到概念图中。然后,我们采用一个框架在知识图谱中自动高精度地检索知识。为了对知识图谱进行合理推理,我们提出了一种上下文推理剪枝算法以实现高效的链式推理。我们的算法分别以92%和96%的精确率和召回率取得了更好的推理结果,能够避免大多数无意义的推理。此外,我们实现了两个原型并提供服务,结果表明我们的方法是实用且有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/17b974bdf140/BMRI2017-2858423.013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/caf48a1206ad/BMRI2017-2858423.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/1fb6e7c72594/BMRI2017-2858423.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/67b5629bee5c/BMRI2017-2858423.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/60c49760e2de/BMRI2017-2858423.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/54034261b849/BMRI2017-2858423.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/30ebab6629c7/BMRI2017-2858423.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/011dcad6513d/BMRI2017-2858423.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/c01c206bcb7f/BMRI2017-2858423.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/fa9a728c442b/BMRI2017-2858423.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/99f022c3cfe0/BMRI2017-2858423.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/ed92055c8114/BMRI2017-2858423.011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/d70d64fcdcb3/BMRI2017-2858423.012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/17b974bdf140/BMRI2017-2858423.013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/caf48a1206ad/BMRI2017-2858423.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/1fb6e7c72594/BMRI2017-2858423.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/67b5629bee5c/BMRI2017-2858423.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/60c49760e2de/BMRI2017-2858423.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/54034261b849/BMRI2017-2858423.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/30ebab6629c7/BMRI2017-2858423.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/011dcad6513d/BMRI2017-2858423.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/c01c206bcb7f/BMRI2017-2858423.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/fa9a728c442b/BMRI2017-2858423.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/99f022c3cfe0/BMRI2017-2858423.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/ed92055c8114/BMRI2017-2858423.011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/d70d64fcdcb3/BMRI2017-2858423.012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7419/5337312/17b974bdf140/BMRI2017-2858423.013.jpg

相似文献

1
Semantic Health Knowledge Graph: Semantic Integration of Heterogeneous Medical Knowledge and Services.语义健康知识图谱:异构医学知识与服务的语义集成
Biomed Res Int. 2017;2017:2858423. doi: 10.1155/2017/2858423. Epub 2017 Feb 12.
2
Semantic web for integrated network analysis in biomedicine.用于生物医学综合网络分析的语义网。
Brief Bioinform. 2009 Mar;10(2):177-92. doi: 10.1093/bib/bbp002.
3
Implementation of a metadata architecture and knowledge collection to support semantic interoperability in an enterprise data warehouse.实施元数据架构和知识收集以支持企业数据仓库中的语义互操作性。
AMIA Annu Symp Proc. 2008 Nov 6:929.
4
Ontology patterns-based transformation of clinical information.基于本体模式的临床信息转换
Stud Health Technol Inform. 2014;205:1018-22.
5
Path-based knowledge reasoning with textual semantic information for medical knowledge graph completion.基于路径的知识推理与文本语义信息融合的医疗知识图谱补全方法
BMC Med Inform Decis Mak. 2021 Nov 29;21(Suppl 9):335. doi: 10.1186/s12911-021-01622-7.
6
Exploiting semantic patterns over biomedical knowledge graphs for predicting treatment and causative relations.利用生物医学知识图谱中的语义模式预测治疗和因果关系。
J Biomed Inform. 2018 Jun;82:189-199. doi: 10.1016/j.jbi.2018.05.003. Epub 2018 May 12.
7
A boosting framework for visuality-preserving distance metric learning and its application to medical image retrieval.一种保持视觉保真度的距离度量学习的提升框架及其在医学图像检索中的应用。
IEEE Trans Pattern Anal Mach Intell. 2010 Jan;32(1):30-44. doi: 10.1109/TPAMI.2008.273.
8
Large scale healthcare data integration and analysis using the semantic web.使用语义网进行大规模医疗保健数据集成与分析。
Stud Health Technol Inform. 2011;169:729-33.
9
Learning semantic and visual similarity for endomicroscopy video retrieval.学习内窥镜视频检索的语义和视觉相似性。
IEEE Trans Med Imaging. 2012 Jun;31(6):1276-88. doi: 10.1109/TMI.2012.2188301. Epub 2012 Feb 16.
10
A cloud-based framework for large-scale traditional Chinese medical record retrieval.基于云的大规模传统中医病历检索框架。
J Biomed Inform. 2018 Jan;77:21-33. doi: 10.1016/j.jbi.2017.11.013. Epub 2017 Nov 22.

引用本文的文献

1
Research on the construction of a knowledge graph for tomato leaf pests and diseases based on the named entity recognition model.基于命名实体识别模型的番茄叶病虫害知识图谱构建研究
Front Plant Sci. 2024 Nov 7;15:1482275. doi: 10.3389/fpls.2024.1482275. eCollection 2024.
2
The importance of graph databases and graph learning for clinical applications.图数据库和图学习在临床应用中的重要性。
Database (Oxford). 2023 Jul 10;2023. doi: 10.1093/database/baad045.
3
Leveraging Knowledge Graphs and Natural Language Processing for Automated Web Resource Labeling and Knowledge Mobilization in Neurodevelopmental Disorders: Development and Usability Study.

本文引用的文献

1
KnowLife: a versatile approach for constructing a large knowledge graph for biomedical sciences.KnowLife:一种构建生物医学科学大型知识图谱的通用方法。
BMC Bioinformatics. 2015 May 14;16:157. doi: 10.1186/s12859-015-0549-5.
2
Watson will see you now: a supercomputer to help clinicians make informed treatment decisions.华生现在可以为您服务了:一台帮助临床医生做出明智治疗决策的超级计算机。
Clin J Oncol Nurs. 2015 Feb;19(1):31-2. doi: 10.1188/15.CJON.31-32.
3
A comprehensive information technology system to support physician learning at the point of care.
利用知识图谱和自然语言处理实现神经发育障碍相关网络资源自动标注和知识转化:开发和可用性研究。
J Med Internet Res. 2023 Apr 17;25:e45268. doi: 10.2196/45268.
4
MLEE: A method for extracting object-level medical knowledge graph entities from Chinese clinical records.最大似然估计法:一种从中文临床记录中提取对象级医学知识图谱实体的方法。
Front Genet. 2022 Jul 22;13:900242. doi: 10.3389/fgene.2022.900242. eCollection 2022.
5
Answering medical questions in Chinese using automatically mined knowledge and deep neural networks: an end-to-end solution.利用自动挖掘的知识和深度神经网络用中文回答医学问题:一种端到端的解决方案。
BMC Bioinformatics. 2022 Apr 15;23(1):136. doi: 10.1186/s12859-022-04658-2.
6
A semantic web technology index.一个语义网技术索引。
Sci Rep. 2022 Mar 7;12(1):3672. doi: 10.1038/s41598-022-07615-4.
7
Personalized Health Knowledge Graph.个性化健康知识图谱
CEUR Workshop Proc. 2018 Oct;2317.
8
Knowledge Extraction of Cohort Characteristics in Research Publications.研究出版物中队列特征的知识提取。
AMIA Annu Symp Proc. 2021 Jan 25;2020:462-471. eCollection 2020.
9
Leveraging graph-based hierarchical medical entity embedding for healthcare applications.基于图的分层医学实体嵌入在医疗保健应用中的应用。
Sci Rep. 2021 Mar 12;11(1):5858. doi: 10.1038/s41598-021-85255-w.
10
Artificial Intelligence Pipeline to Bridge the Gap between Bench Researchers and Clinical Researchers in Precision Medicine.人工智能管道弥合精准医学基础研究人员与临床研究人员之间的差距。
Med One. 2020 Jan 10;5. doi: 10.20900/mo20200001.
一个全面的信息技术系统,以支持医生在医疗护理点的学习。
Acad Med. 2015 Jan;90(1):33-9. doi: 10.1097/ACM.0000000000000551.
4
Improving data and knowledge management to better integrate health care and research.改善数据和知识管理,以更好地整合医疗保健与研究。
J Intern Med. 2013 Oct;274(4):321-8. doi: 10.1111/joim.12105. Epub 2013 Jul 15.
5
Creating personalised clinical pathways by semantic interoperability with electronic health records.通过与电子健康记录的语义互操作性创建个性化临床路径。
Artif Intell Med. 2013 Jun;58(2):81-9. doi: 10.1016/j.artmed.2013.02.005. Epub 2013 Mar 5.
6
Next-generation phenotyping of electronic health records.电子健康记录的下一代表型分析。
J Am Med Inform Assoc. 2013 Jan 1;20(1):117-21. doi: 10.1136/amiajnl-2012-001145. Epub 2012 Sep 6.
7
Steps towards a digital health ecosystem.迈向数字健康生态系统的步骤。
J Biomed Inform. 2011 Aug;44(4):621-36. doi: 10.1016/j.jbi.2011.02.011. Epub 2011 Feb 27.
8
Toward an ontological treatment of disease and diagnosis.迈向疾病与诊断的本体论治疗。
Summit Transl Bioinform. 2009 Mar 1;2009:116-20.
9
Effective knowledge management in translational medicine.转化医学中的有效知识管理。
J Transl Med. 2010 Jul 19;8:68. doi: 10.1186/1479-5876-8-68.
10
Creating and sharing clinical decision support content with Web 2.0: Issues and examples.利用Web 2.0创建和共享临床决策支持内容:问题与实例
J Biomed Inform. 2009 Apr;42(2):334-46. doi: 10.1016/j.jbi.2008.09.003. Epub 2008 Oct 8.