Toyoda Shigeru, Takekawa Hidehiro, Asakawa Yohei, Suzuki Ayano, Otani Naoyuki, Sakuma Masashi, Abe Shichiro, Hirata Koichi, Inoue Teruo
Department of Cardiovascular Medicine, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan.
Stroke Division, Department of Neurology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan.
J Med Ultrason (2001). 2018 Jan;45(1):149-154. doi: 10.1007/s10396-017-0781-x. Epub 2017 Mar 15.
Although risk factors for acute coronary syndrome (ACS) and atherothrombotic cerebral infarction (ACI) are common, it is unknown if the risk factors for these two conditions are similar. The purpose of our study was to elucidate differences in carotid artery atherosclerotic features between ACS and ACI.
We measured carotid artery ultrasound-based atherosclerotic parameters in 61 ACS and 33 ACI patients. In the ACS patients, 31 had single-vessel coronary artery disease (SVD) and 30 had multivessel coronary artery disease (MVD).
The maximum intima-media thickness (IMT) of the common carotid artery was higher in ACS patients with MVD than in ACS patients with SVD (P < 0.05), and tended to be higher than that in ACI patients (P = 0.085). The values in ACS patients with SVD and ACI patients were similar. The maximum IMT of the carotid artery bulb in ACS patients with MVD was similar to that in both ACS patients with SVD and ACI patients. The plaque score was higher in ACS patients with MVD than in ACS patients with SVD (P < 0.01), but similar to that in ACI patients.
ACS and ACI show common atherosclerotic features as assessed by carotid artery ultrasonography.
尽管急性冠状动脉综合征（ACS）和动脉粥样硬化性脑梗死（ACI）的危险因素有共同之处，但这两种疾病的危险因素是否相似尚不清楚。我们研究的目的是阐明ACS和ACI之间颈动脉粥样硬化特征的差异。
我们测量了61例ACS患者和33例ACI患者基于颈动脉超声的动脉粥样硬化参数。在ACS患者中，31例患有单支冠状动脉疾病（SVD），30例患有多支冠状动脉疾病（MVD）。
患有MVD的ACS患者的颈总动脉最大内膜中层厚度（IMT）高于患有SVD的ACS患者（P<0.05），且有高于ACI患者的趋势（P=0.085）。患有SVD的ACS患者和ACI患者的该值相似。患有MVD的ACS患者的颈动脉球部最大IMT与患有SVD的ACS患者和ACI患者的相似。患有MVD的ACS患者的斑块评分高于患有SVD的ACS患者（P<0.01），但与ACI患者的相似。
通过颈动脉超声评估，ACS和ACI表现出共同的动脉粥样硬化特征。
