Betoko A, Lioret S, Heude B, Hankard R, Carles S, Forhan A, Regnault N, Botton J, Charles M A, de Lauzon-Guillain B
INSERM, UMR1153 Epidemiology and Biostatistics Sorbonne Paris Cité Center (CRESS), ORCHAD Team, Paris, France.
Paris Descartes University, Paris, France.
Pediatr Obes. 2017 Aug;12 Suppl 1:94-101. doi: 10.1111/ijpo.12213. Epub 2017 Mar 15.
As early-life feeding experiences may influence later health, we aimed to examine relations between feeding patterns over the first year of life and child's growth in the first 5 years of life.
Our analysis included 1022 children from the EDEN mother-child cohort. Three feeding patterns were previously identified, i.e. 'Later dairy products introduction and use of ready-prepared baby foods' (pattern-1), 'Long breastfeeding, later main meal food introduction and use of home-made foods' (pattern-2) and 'Use of ready-prepared adult foods' (pattern-3). Associations between the feeding patterns and growth [weight, height and body mass index {BMI}] were analysed by multivariable linear regressions. Anthropometric changes were assessed by the final value adjusted for the initial value.
Even though infant feeding patterns were not related to anthropometric measurements at 1, 3 and 5 years, high scores on pattern-1 were associated with higher 1-3 years weight and height changes. High scores on pattern-2 were related to lower 0-1 year weight and height changes, higher 1-5 years weight and height changes but not to BMI changes, after controlling for a wide range of potential confounding variables including parental BMI. Scores on pattern-3 were not significantly related to growth. Additional adjustment for breastfeeding duration reduced the strength of the associations between pattern-2 and growth but not those between pattern-1 and height growth.
Our findings emphasize the relevance of considering infant feeding patterns including breastfeeding duration, age of complementary foods introduction as well as type of foods used when examining effects of early infant feeding practices on later health. © 2017 World Obesity Federation.
由于生命早期的喂养经历可能会影响后期健康，我们旨在研究生命第一年的喂养模式与儿童五岁前生长发育之间的关系。
我们的分析纳入了来自EDEN母婴队列的1022名儿童。先前已确定了三种喂养模式，即“较晚引入乳制品并使用即食婴儿食品”（模式1）、“长时间母乳喂养、较晚引入主餐食物并使用自制食品”（模式2）和“使用即食成人食品”（模式3）。通过多变量线性回归分析喂养模式与生长指标[体重、身高和体重指数（BMI）]之间的关联。人体测量变化通过对初始值进行调整后的最终值进行评估。
尽管婴儿喂养模式与1岁、3岁和5岁时的人体测量指标无关，但模式1得分高与1至3岁时较高的体重和身高变化相关。在控制了包括父母BMI在内的一系列潜在混杂变量后，模式2得分高与0至1岁时较低的体重和身高变化、1至5岁时较高的体重和身高变化相关，但与BMI变化无关。模式3得分与生长发育无显著关联。对母乳喂养持续时间进行额外调整后，模式2与生长之间的关联强度降低，但模式1与身高生长之间的关联强度未降低。
我们的研究结果强调了在研究婴儿早期喂养方式对后期健康的影响时，考虑婴儿喂养模式（包括母乳喂养持续时间、辅食引入年龄以及所使用食物的类型）的重要性。©2017世界肥胖联合会。
