Baggio Raphaëlle, Le Treut Claire, Darrieux Laure, Vareliette Amélie, Safa Gilles
Department of Dermatology, Centre Hospitalier de Saint-Brieuc, Saint-Brieuc, France.
Department of Pediatrics, Centre Hospitalier de Saint-Brieuc, Saint-Brieuc, France.
Case Rep Dermatol. 2016 Dec 22;8(3):369-373. doi: 10.1159/000455021. eCollection 2016 Sep-Dec.
Propranolol, a nonselective blocker of β-adrenergic receptors, has become the first-line treatment for complicated infantile hemangiomas. Therefore, its use in the pediatric population has expanded in recent years. In adults, β-blockers have been reported to be the most common causative agents for drug-induced psoriasis. In infants treated with propranolol for infantile hemangioma, the onset of psoriasiform diaper rash has not yet been reported. Here, to the best of our knowledge, we report the first case of psoriasiform diaper rash possibly induced by oral propranolol in an 18-month-old girl with no family history of psoriasis.
普萘洛尔是一种非选择性β-肾上腺素能受体阻滞剂，已成为治疗复杂性婴儿血管瘤的一线药物。因此，近年来其在儿科人群中的应用有所扩大。在成人中，β受体阻滞剂据报道是药物性银屑病最常见的致病因素。在接受普萘洛尔治疗婴儿血管瘤的婴儿中，尚未有银屑病样尿布疹发作的报道。在此，据我们所知，我们报告了首例可能由口服普萘洛尔诱发的银屑病样尿布疹病例，患儿为一名18个月大的女童，无银屑病家族史。
