Härter Jéssica, Orlandi Silvana Paiva, Gonzalez Maria Cristina
Post-graduate Program, Nutrition and Food, Federal University of Pelotas, Rua Gomes Carneiro, 01, Pelotas, RS, 96010-610, Brazil.
Post-graduate Program, Health and Behavioral, Catholic University of Pelotas, Rua Gonçalves Chaves, 373, Pelotas, RS, 96015-560, Brazil.
Support Care Cancer. 2017 Aug;25(8):2525-2530. doi: 10.1007/s00520-017-3661-4. Epub 2017 Mar 16.
We evaluated phase angle, sarcopenia, and handgrip strength as prognostic factors of postoperative morbimortality in patients with cancer.
We conducted a prospective study with 60 oncology patients admitted for elective surgery between November 2015 and May 2016. We calculated the standardized phase angle (SPA) and the skeletal mass index of the subjects based on their bioelectrical impedance tests. Handgrip strength (HGS) was measured using a hydraulic dynamometer. Diagnosis of sarcopenia followed the criteria of the European Working Group on Sarcopenia in Older People. The nutritional status of each subject was evaluated through the Patient-Generated Subjective Global Assessment. Evaluation of postoperative complications followed the Clavien-Dindo classification. We also evaluated the duration of hospital stay. Outcomes were postoperative complications and duration of hospital stay.
The prevalence of malnutrition was 28.3%, and the prevalence of sarcopenia was 18.6%. The SPA was significantly lower among those who had severe postoperative complications or long hospital stays, while HGS and sarcopenia showed no relationship with these outcomes. Malnutrition was also related to postoperative outcomes.
SPA can be considered a prognostic factor in postoperative morbimortality for patients with cancer.
我们评估了相位角、肌肉减少症和握力作为癌症患者术后病死率的预后因素。
我们对2015年11月至2016年5月期间因择期手术入院的60名肿瘤患者进行了一项前瞻性研究。我们根据受试者的生物电阻抗测试计算了标准化相位角（SPA）和骨骼肌质量指数。使用液压测力计测量握力（HGS）。肌肉减少症的诊断遵循欧洲老年人肌肉减少症工作组的标准。通过患者自主主观整体评估来评估每个受试者的营养状况。术后并发症的评估遵循Clavien-Dindo分类法。我们还评估了住院时间。结果是术后并发症和住院时间。
营养不良的患病率为28.3%，肌肉减少症的患病率为18.6%。在发生严重术后并发症或住院时间长的患者中，SPA显著较低，而HGS和肌肉减少症与这些结果无关。营养不良也与术后结果相关。
SPA可被视为癌症患者术后病死率的一个预后因素。
