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在接受全髋关节置换术的重度单侧原发性髋骨关节炎患者中,股骨颈前倾角导致的脊柱骨盆参数变化及腰痛改善情况

Spinopelvic parameter changes and low back pain improvement due to femoral neck anteversion in patients with severe unilateral primary hip osteoarthritis undergoing total hip replacement.

作者信息

Piazzolla Andrea, Solarino Giuseppe, Bizzoca Davide, Montemurro Viola, Berjano Pedro, Lamartina Claudio, Martini Carlotta, Moretti Biagio

机构信息

School of Medicine, University of Bari Aldo Moro, AOU Consorziale Policlinico, Department of Basic Medical Sciences, Neuroscience and Sense Organs, Orthopaedic, Trauma and Spine Unit, Piazza Giulio Cesare 11, 70100, Bari, Italy.

GSpine4, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

出版信息

Eur Spine J. 2018 Jan;27(1):125-134. doi: 10.1007/s00586-017-5033-7. Epub 2017 Mar 16.

Abstract

PURPOSE

The study of the interrelation between hip and spine disorders is gaining increasing importance in the last years, but the link between Hip Osteoarthritis (HOA) and Low Back Pain (LBP) remains still unclear. Aim of the study is to assess the relationship between Femoral Neck Anteversion (FNA), LBP, and spinopelvic parameters in patients undergoing Total Hip Replacement (THR) for unilateral severe primary HOA.

MATERIALS AND METHODS

91 patients were recruited. Inclusion criteria were: grade 5 or 6 unilateral HOA, according to Turmezei, and Harris Hip score (HHS) <60. Exclusion criteria were: secondary hip osteoarthritis (dysplasia of the hip, rheumatoid arthritis, and ankylosing spondylitis); previous surgery of the spine, hip or knee; scoliosis with a Cobb angle greater than 10°; spondylolisthesis; history of spine fractures; previous bone tuberculosis or any spine infections; any contraindications to CT; BMI >30. Patients were divided into two homogeneous Groups according to the presence (Group-A) or not of concomitant LBP (Group-B). All patients underwent preoperatively a hip CT scan to evaluate FNA, Acetabular Anteversion (AA), and Combined Anteversion (CA = FNA + AA). ΔFNA, ΔAA and ΔCA were calculated as the differences between the arthritic hip and the normal hip angles in each Group. Full spinal X-rays in upstanding position were performed before (baseline) and 6 months after THR (follow-up) to calculate spinopelvic parameters. The health-related quality of life (HRQoL) was evaluated at baseline and at follow-up using Visual Analogue Scale (VAS), HHS, Oswestry Disability Index (ODI), Roland-Morris Disability Questionnaire (RM), and Short-Form Health Survey (SF-36). The intra-group and inter-group variability were assessed using, respectively, paired and unpaired t tests. At baseline, the association between HRQoL scores and ΔFNA, ΔAA, and ΔCA was analysed by the Pearson correlation test.

RESULTS

At baseline, in Group-A, there was a significant difference between arthritic FNA and normal hip FNA, while no differences were found in AA between the two hips. A close correlation was observed between ΔFNA and Spine-VAS (r = 0.788), ODI (r = 0.824), and RM (r = 0.775). In Group-B, there was not a significant difference in FNA and AA between the two hips. At recruitment, in Group-A patients, we recorded a higher LL, SS, PI, SVA(C7), and a lower PT and T1-SPI compared with Group-B subjects. Six months after THR, in Group-A, an improvement of all clinical scores was recorded, as well as, a significant reduction of SS, LL, T1PA, and SVA(C7) and an increment of PT. In Group-B, at follow-up, an improvement of HHS, Hip-VAS, and SF-36 was recorded, while the changes in spinopelvic parameters were not significant.

CONCLUSIONS

Patients with concomitant unilateral HOA and LBP showed a marked anteverted FNA in the arthritic hip and a spinopelvic misalignment. After THR, a relief of both hip and low back pain and a change in spinopelvic parameters is observed.

摘要

目的

近年来,髋部与脊柱疾病之间相互关系的研究愈发重要,但髋骨关节炎(HOA)与下腰痛(LBP)之间的联系仍不明确。本研究旨在评估单侧严重原发性HOA患者行全髋关节置换术(THR)时,股骨颈前倾角(FNA)、LBP与脊柱骨盆参数之间的关系。

材料与方法

招募91例患者。纳入标准为:根据Turmezei分级为5级或6级单侧HOA,且Harris髋关节评分(HHS)<60。排除标准为:继发性髋骨关节炎(髋关节发育不良、类风湿关节炎和强直性脊柱炎);既往有脊柱、髋部或膝关节手术史;Cobb角大于10°的脊柱侧弯;椎体滑脱;脊柱骨折史;既往骨结核或任何脊柱感染;CT检查的任何禁忌症;体重指数(BMI)>30。根据是否伴有LBP将患者分为两组(A组)和无LBP组(B组)。所有患者术前均行髋部CT扫描以评估FNA、髋臼前倾角(AA)和联合前倾角(CA = FNA + AA)。计算ΔFNA、ΔAA和ΔCA,即每组中患侧髋关节与正常髋关节角度的差值。在THR术前(基线)和术后6个月(随访)进行站立位全脊柱X线检查,以计算脊柱骨盆参数。使用视觉模拟量表(VAS)、HHS、Oswestry功能障碍指数(ODI)、Roland-Morris功能障碍问卷(RM)和简短健康调查问卷(SF-36)在基线和随访时评估健康相关生活质量(HRQoL)。分别使用配对t检验和独立样本t检验评估组内和组间差异。在基线时,通过Pearson相关检验分析HRQoL评分与ΔFNA、ΔAA和ΔCA之间的相关性。

结果

基线时,A组患侧髋关节FNA与正常髋关节FNA之间存在显著差异,而双侧髋关节AA无差异。观察到ΔFNA与脊柱VAS(r = 0.788)、ODI(r = 0.824)和RM(r = 0.775)之间密切相关。在B组中,双侧髋关节FNA和AA无显著差异。招募时,与B组受试者相比,A组患者的腰椎前凸(LL)、骶骨倾斜角(SS)、骨盆入射角(PI)、C7矢状面垂直轴(SVA(C7))较高,骨盆倾斜角(PT)和T1-SPI较低。THR术后6个月,A组所有临床评分均有改善,SS、LL、T1骨盆倾斜角(T1PA)和SVA(C7)显著降低,PT增加。在B组,随访时HHS、髋关节VAS和SF-36有所改善,而脊柱骨盆参数变化不显著。

结论

伴有单侧HOA和LBP的患者患侧髋关节FNA明显前倾,且存在脊柱骨盆失准。THR术后,髋部和下腰痛均得到缓解,脊柱骨盆参数发生变化。

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