Chromosome replication in Escherichia coli induced by oversupply of DnaA.
作者信息
Xu Y C, Bremer H
机构信息
Biology Programs, University of Texas at Dallas, Richardson 75080.
出版信息
Mol Gen Genet. 1988 Jan;211(1):138-42. doi: 10.1007/BF00338404.
PMID:2830461
Abstract
Overexpression of DnaA protein from a multicopy plasmid accompanied by a shift to 42 degrees C causes initiation of one extra round of replication in a dnaA+ strain grown in glycerol minimal medium. This extra round of replication does not lead to an extra cell division, such that cells contain twice the normal number of chromosomes.
摘要
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