• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

N-乙基脲烷对饰纹姬蛙胚胎早期发育及核酸代谢的影响

The influence of N-ethyl urethane on the early development and nucleic acid metabolism in the embryos ofMicrohyla ornata.

作者信息

Joshi Sanjivani S

机构信息

Department of Zoology, University of Poona, India.

出版信息

Wilhelm Roux Arch Entwickl Mech Org. 1967 Jun;158(2):188-194. doi: 10.1007/BF00574019.

DOI:10.1007/BF00574019
PMID:28304643
Abstract
  1. The effects of N-ethyl urethane on the development ofMicrohyla ornata have been studied. 2. The embryos treated at early gastrula stage showed a disorganization and lack of differentiation of various organs. A range of abnormalities includes oedema, dwarfism, bent trunk or tail, brain and eye defects. 3. However, when urethane (0.4%) treated embryos received a subsequent thymidine treatment (6×10 M) they showed a remarkable improvement in the development of various organs. 4. The possible mode of action of urethane and its relationship with nucleic acid metabolism has been discussed.
摘要
  1. 已对N-乙基脲烷对饰纹姬蛙发育的影响进行了研究。2. 在原肠胚早期阶段处理的胚胎表现出各种器官的紊乱和分化缺失。一系列异常包括水肿、侏儒症、躯干或尾巴弯曲、脑和眼缺陷。3. 然而,当用脲烷(0.4%)处理的胚胎接受随后的胸苷处理(6×10⁻⁶M)时,它们在各种器官的发育上表现出显著改善。4. 已讨论了脲烷可能的作用方式及其与核酸代谢的关系。

相似文献

1
The influence of N-ethyl urethane on the early development and nucleic acid metabolism in the embryos ofMicrohyla ornata.N-乙基脲烷对饰纹姬蛙胚胎早期发育及核酸代谢的影响
Wilhelm Roux Arch Entwickl Mech Org. 1967 Jun;158(2):188-194. doi: 10.1007/BF00574019.
2
A study of the mechanism of action of colchicine on embryos ofMicrohyla ornata.秋水仙碱对饰纹姬蛙胚胎作用机制的研究。
Wilhelm Roux Arch Entwickl Mech Org. 1967 Jun;158(2):164-169. doi: 10.1007/BF00574017.
3
Dependence of the timing system regulating the onset of gastrulation on cytoplasmic, but not nuclear, activities in the Xenopus embryo.非洲爪蟾胚胎中调节原肠胚形成起始的计时系统对细胞质而非细胞核活动的依赖性。
Dev Growth Differ. 2005 Aug;47(6):415-22. doi: 10.1111/j.1440-169X.2005.00808.x.
4
Analysis of the embryonic phenotype of Bent tail, a mouse model for X-linked neural tube defects.对弯尾小鼠胚胎表型的分析,一种X连锁神经管缺陷的小鼠模型。
Anat Embryol (Berl). 2003 Oct;207(3):255-62. doi: 10.1007/s00429-003-0345-2. Epub 2003 Oct 2.
5
Radiation-induced abnormalities in the chick embryos treated with urethane.用氨基甲酸乙酯处理的鸡胚中的辐射诱导异常。
Wilhelm Roux Arch Entwickl Mech Org. 1968 Dec;161(4):319-324. doi: 10.1007/BF00576683.
6
A role for DNA methylation in gastrulation and somite patterning.DNA甲基化在原肠胚形成和体节模式形成中的作用。
Dev Biol. 1999 Feb 15;206(2):189-205. doi: 10.1006/dbio.1998.9105.
7
Direct effects of retinoic acid on the development of the tail bud in chick embryos.
Teratology. 1989 Mar;39(3):261-75. doi: 10.1002/tera.1420390308.
8
[Effect of some N-alkyl-N-NO-carbamyl esters on leukemia L 5222].
Arzneimittelforschung. 1975 Apr;25(4):577-80.
9
[Characteristics of the proliferative activity of the aggregates forming during recombination of the epithelium and mesenchyma of embryonic lungs from intact and carcinogen-treated mice].[来自完整和致癌物处理小鼠胚胎肺上皮与间充质重组过程中形成的聚集体的增殖活性特征]
Ontogenez. 1984 Sep-Oct;15(5):522-8.
10
[Urethane inhibition of DNA synthesis in the hepatocytes of the regenerating liver in mice].[氨基甲酸乙酯对小鼠再生肝肝细胞DNA合成的抑制作用]
Tsitologiia. 1985 Oct;27(10):1145-9.

引用本文的文献

1
Radiation-induced abnormalities in the chick embryos treated with urethane.用氨基甲酸乙酯处理的鸡胚中的辐射诱导异常。
Wilhelm Roux Arch Entwickl Mech Org. 1968 Dec;161(4):319-324. doi: 10.1007/BF00576683.

本文引用的文献

1
The effect of inhibitory substances on cell division; a study on living cells in tissue cultures.
Q J Microsc Sci. 1950 Sep;91(3):251-77.
2
Effects of urethane on mitosis in the Walker rat carcinoma.氨基甲酸乙酯对沃克大鼠癌有丝分裂的影响。
Br J Cancer. 1954 Dec;8(4):677-84. doi: 10.1038/bjc.1954.73.
3
The influence of folic acid analogs on development and nucleic acid metabolism in Rana pipiens embryos.叶酸类似物对豹蛙胚胎发育和核酸代谢的影响。
Dev Biol. 1960 Jun;2:197-251. doi: 10.1016/0012-1606(60)90007-5.
4
Studies of the mechanism of action of urethane in initiating pulmonary adenomas in mice. II. Its relation to nucleic acid synthesis.氨基甲酸乙酯诱发小鼠肺腺瘤作用机制的研究。II. 其与核酸合成的关系。
J Exp Med. 1957 Apr 1;105(4):279-306. doi: 10.1084/jem.105.4.279.
5
Conversion of uracil deoxyriboside to thymidine of deoxyribonucleic acid.尿嘧啶脱氧核糖核苷向脱氧核糖核酸的胸腺嘧啶核苷的转化。
J Biol Chem. 1956 Jun;220(2):653-60.
6
Effects of ethyl carbamate (urethan) and related compounds on early developmental processes of the leopard frog, Rana pipiens.氨基甲酸乙酯(尿烷)及相关化合物对豹蛙(北美林蛙)早期发育过程的影响。
Cancer Res. 1954 May;14(4):319-23.