Lee Barber Mary
Biology Department, San Fernando Valley State College, 91324, Northridge, California.
Wilhelm Roux Arch Entwickl Mech Org. 1971 Sep;166(3):226-235. doi: 10.1007/BF00650032.
Sea urchin development is inhibited in the presence of mycostatin, a fungicidal antibiotic believed to alter cell membranes. Pretreatment of eggs inhibits fertilization inL. pictus, but not inS. purpuratus. The doses resulting in abnormal development inS. purpuratus increase as the treatment is started later in development. AH tissues are sensitive to mycostatin at high concentrations, but the endodermal and mesenchyme derivatives are most sensitive at lower concentrations. The results suggest the heterogeneity of cell membranes and also indicate that membranes change with time of development.
在制霉菌素存在的情况下，海胆的发育受到抑制。制霉菌素是一种杀真菌抗生素，据信会改变细胞膜。卵的预处理会抑制紫球海胆的受精，但不会抑制紫海胆的受精。随着处理在发育后期开始，导致紫海胆发育异常的剂量会增加。高浓度时所有组织对制霉菌素敏感，但内胚层和间充质衍生物在较低浓度时最敏感。结果表明细胞膜具有异质性，也表明细胞膜会随发育时间而变化。
