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细胞克隆与模式形成:黑腹果蝇中的遗传眼镶嵌体

Cell clones and pattern formation: Genetic eye mosaics inDrosophila melanogaster.

作者信息

Hofbauer Alois, Campos-Ortega J A

机构信息

Institut für Biologie III, Schänzlestraße 9-11, D-7800, Freiburg i.Br., Federal Republic of Germany.

出版信息

Wilehm Roux Arch Dev Biol. 1976 Dec;179(4):275-289. doi: 10.1007/BF00848237.

Abstract

Genetic eye mosaics ofDrosophila melanogaster have been studied by means of anatomical techniques. Using different cell markers it was found that the ommatidia at the boundaries between phenotypes are composed of cells belonging to different clones. Therefore, the formation of an individual ommatidium does not obey a mechanism based on a common clonal origin of its constituent elements. A statistical analysis of mosaic ommatidia shows that there is a significant tendency for the receptor cellsR2-R5 on the one hand and the receptor cellsR1, R6 andR7 on the other to belong to the same cell clone. The implications of these findings are discussed.

摘要

已通过解剖学技术对黑腹果蝇的遗传眼嵌合体进行了研究。利用不同的细胞标记发现,表型边界处的小眼由属于不同克隆的细胞组成。因此,单个小眼的形成并不遵循基于其组成元件共同克隆起源的机制。对嵌合小眼的统计分析表明,一方面,受体细胞R2 - R5与另一方面的受体细胞R1、R6和R7有显著的倾向属于同一细胞克隆。讨论了这些发现的意义。

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