Miñana F J, García-Bellido A
Centro de Biologia Molecular, Consejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid, Canto Blanco, Madrid-34, Spain.
Wilehm Roux Arch Dev Biol. 1982 Sep;191(5):331-334. doi: 10.1007/BF00848493.
InDrosophila melanogaster, segmental specification takes place in groups of cells around the blastoderm stage. This segmental specification requires the function of the genes of the bithorax-complex. We have studied preblastoderm mosaics (gynandromorphs) of mutant (bx ,pbx, Ubx, Ubx ) and wildtype (heterozygotes for these alleles) cells. The results show a total cell autonomy in the differentiation of both wildtype and homoeotially transformed cells. However, several unexpected phenotypes were found. They are discussed in terms of the function of the bithorax genes and early interactions between mutant and wildtype territories.
在黑腹果蝇中，体节特化发生在胚盘阶段周围的细胞群中。这种体节特化需要双胸复合体基因的功能。我们研究了突变型（bx、pbx、Ubx、Ubx）和野生型（这些等位基因的杂合子）细胞的胚盘前镶嵌体（雌雄嵌合体）。结果表明，野生型细胞和同源异型转化细胞在分化过程中都具有完全的细胞自主性。然而，发现了几种意外的表型。根据双胸基因的功能以及突变型和野生型区域之间的早期相互作用对这些表型进行了讨论。
