一种控制黑腹果蝇有丝分裂染色体分离的新突变体。
A new mutant controlling mitotic chromosome disjunction in Drosophila melanogaster.
作者信息
Gelbart W M
出版信息
Genetics. 1974 Jan;76(1):51-63. doi: 10.1093/genetics/76.1.51.
Abstract
A new mutant, mit (mitotic loss inducer), is described. The mutant is recessive and maternal in action, producing gynandromorphs and haplo-4 mosaics among the progeny of homozygous mit females. Mosaic loss of maternal or paternal chromosomes can occur. The probabilities of either maternal or paternal X chromosome loss are equal. mit has been mapped to approximately 57 on the standard X chromosome map.-Using gyandromorphs generated by mit, a morphogenetic fate map, placing the origins of 40 cuticular structures on the blastoderm surface, has been constructed. This fate map is consistent with embryological data and with the two other fate maps generated in different ways.
摘要
描述了一种新的突变体mit（有丝分裂损失诱导剂）。该突变体是隐性的，起母体作用，在纯合mit雌性的后代中产生雌雄嵌合体和单倍体-4嵌合体。母本或父本染色体可能会发生嵌合性丢失。母本或父本X染色体丢失的概率相等。mit已定位到标准X染色体图谱上大约57的位置。利用mit产生的雌雄嵌合体，构建了一个形态发生命运图谱，将40种表皮结构的起源定位在胚盘表面。该命运图谱与胚胎学数据以及以不同方式生成的其他两个命运图谱一致。
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