Knibiehler Bernard, Mirre Christian, Cecchini Jean -Pierre, Le Parco Yannick
Faculté des Sciences de Luminy, Laboratoire de Biologie de la Différenciation Cellulaire, Case 901, F-13288, Marseille Cedex 9, France.
Rouxs Arch Dev Biol. 1987 Apr;196(4):243-247. doi: 10.1007/BF00376348.
We report a direct examination of the expression of one collagen gene (DCg1) during Drosophila melanogaster metamorphosis, based on data from in situ hybridization. The transcripts of this gene, thought to encode a basement membrane type IV collagen, are mainly accumulated during ecdysis in wandering haemocytes. Our results demonstrate that haemocytes contribute to extracellular matrix deposition and seem to perform a fibroblastic function during Drosophila development.
基于原位杂交数据,我们报告了对果蝇变态过程中一种胶原蛋白基因(DCg1)表达的直接检测。该基因的转录本被认为编码一种基底膜IV型胶原蛋白,主要在化蛹期的游走血细胞中积累。我们的结果表明,血细胞有助于细胞外基质沉积,并且在果蝇发育过程中似乎发挥着成纤维细胞的功能。