Hinderliter C F, Misanin J R
University of Pittsburgh at Johnstown 15904.
Behav Neural Biol. 1988 Jan;49(1):112-7. doi: 10.1016/s0163-1047(88)91297-6.
Weanling, young-adult, and senescent Wistar albino rats had a novel odor/taste stimulus or a single taste stimulus either paired or explicitly unpaired with the unconditioned stimulus, lithium chloride. Animals were then given a saccharin vs water preference test. Standard preference scores indicated that the odor competed with taste for association with the US in young-adult rats but potentiated the conditioned aversion to taste in weanling and senescent rats. Results were interpreted in terms of age-related attentional differences which were hypothesized to account for infantile amnesia and for the memory dysfunction typically observed in senescent animals.
断乳期、青年期和老年期的Wistar白化大鼠接受了一种新的气味/味道刺激或单一味道刺激,该刺激与非条件刺激氯化锂进行配对或明确不配对。然后给动物进行糖精与水的偏好测试。标准偏好分数表明,在青年大鼠中,气味与味道竞争与非条件刺激的关联,但在断乳期和老年大鼠中,气味增强了对味道的条件性厌恶。结果根据与年龄相关的注意力差异进行解释,这些差异被假设为导致婴儿期遗忘症以及老年动物中通常观察到的记忆功能障碍的原因。