APOL1：用遗传学取代种族的一个典型例子。

APOL1: a case in point for replacing race with genetics.

机构信息

Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

出版信息

Kidney Int. 2017 Apr;91(4):768-770. doi: 10.1016/j.kint.2017.02.002.

DOI:10.1016/j.kint.2017.02.002

Abstract

Ethnicity-specific differences in apolipoprotein L1 (APOL1) polymorphisms are associated with racial disparities in kidney transplantation outcomes. APOL1 genotyping may better help define graft outcome risk pre-transplantation; however, more research is needed.

摘要

载脂蛋白 L1(APOL1)多态性的种族特异性差异与肾移植结局的种族差异有关。APOL1 基因分型可能有助于更好地在移植前定义移植物结局风险；但是，还需要更多的研究。