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关于对原发性肾脏活检标本中慢性改变进行标准化分级的建议。

A proposal for standardized grading of chronic changes in native kidney biopsy specimens.

出版信息

Kidney Int. 2017 Apr;91(4):787-789. doi: 10.1016/j.kint.2017.01.002.

DOI:10.1016/j.kint.2017.01.002
PMID:28314581
Abstract

Chronic changes represent an important component of native kidney biopsy evaluation and have a major bearing on predicting prognosis and guiding treatment. We propose here a uniform, semiquantitative approach to assessing such changes, which include glomerulosclerosis, tubular atrophy, interstitial fibrosis, and arteriosclerosis, and we report these findings as an overall chronicity grade.

摘要

慢性改变是评估原发性肾脏活检的重要组成部分,对预测预后和指导治疗具有重要意义。在此,我们提出了一种评估这些改变的统一、半定量方法,包括肾小球硬化、肾小管萎缩、间质纤维化和动脉硬化,并将这些发现报告为一个整体的慢性程度等级。

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