Northwestern Medicine, Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Neuro Oncol. 2018 Nov 9;20(suppl_7):vii27-vii39. doi: 10.1093/neuonc/noy100.
Survival alone is no longer an adequate outcome for persons with brain tumors; the quality of the survivorship experience should be viewed with equal importance. Symptom management is a significant component of quality survivorship care. Regardless of their histology, brain tumors and therapies used to treat them produce symptoms that affect an individual's ability to function in everyday life. Common symptoms include fatigue, cognitive impairment, distress, and sleep disturbance. Symptom-based interventions for persons with brain tumors focus on prevention, self-management, and prescriptive interventions targeted to these problems. Unfortunately, little evidence exists to support many interventions, making it challenging for clinicians to provide concrete recommendations. Research is needed to provide evidence in support of symptom-based interventions while novel approaches to these challenging problems are developed.
仅生存本身已不再是脑肿瘤患者的充分治疗目标；生存质量也应得到同等重视。症状管理是高质量生存护理的重要组成部分。无论脑肿瘤的组织学类型如何，以及用于治疗脑肿瘤的疗法如何，这些都会产生影响个体日常生活功能的症状。常见的症状包括疲劳、认知障碍、痛苦和睡眠障碍。针对脑肿瘤患者的基于症状的干预措施侧重于预防、自我管理和针对这些问题的规定性干预措施。遗憾的是，很少有证据支持许多干预措施，这使得临床医生难以提供具体的建议。需要开展研究，为基于症状的干预措施提供证据支持，同时开发针对这些具有挑战性问题的新方法。
