Correia Sofia O, Santos Sofia, Malheiro Jorge, Cabrita António, Martins La Salete, Santos Josefina
Sofia O Correia, Sofia Santos, Jorge Malheiro, António Cabrita, La Salete Martins, Josefina Santos, Nephrology and Transplant Department, Centro Hospitalar do Porto, 4099-001 Porto, Portugal.
World J Nephrol. 2017 Mar 6;6(2):72-78. doi: 10.5527/wjn.v6.i2.72.
The clinical spectrum of diseases associated with monoclonal gammopathies is wide and they are most commonly the consequence of renal deposition of monoclonal immunoglobulin or its components. The differential diagnosis is difficult and renal biopsy is essential. To distinguish many of these pathologies is necessary to use techniques that are not always available, even in tertiary central hospitals. This review will discuss the clinical presentation, pathologic features, treatment, prognosis and common diagnostic difficulties of these entities.
与单克隆丙种球蛋白病相关的疾病临床谱广泛，它们最常见的原因是单克隆免疫球蛋白或其成分在肾脏沉积。鉴别诊断困难，肾活检至关重要。要区分其中许多病理情况，需要使用一些即使在三级中心医院也并非总能获得的技术。本综述将讨论这些疾病的临床表现、病理特征、治疗、预后及常见的诊断难点。
