The University of Tennessee - Knoxville College of Veterinary Medicine, Department of Large Animal Clinical Sciences (Garcia, Smith, Mulon) and Department of Biomedical and Diagnostic Sciences (Fry), 2407 River Drive, Knoxville, Tennessee 37996, USA; Iowa State University, College of Veterinary Medicine, Department of Biomedical Sciences, 1800 Christensen Drive, Ames, Iowa 50011, USA (Smith).
Can Vet J. 2023 May;64(5):419-425.
This retrospective study describes clinical presentation, diagnostic approach, treatment, and outcome for goats with presumptive cerebrospinal nematodiasis. A presumptive diagnosis was made based on neurologic signs, results of cerebrospinal fluid analysis, and response to treatment. Six goats were identified that met inclusion criteria. Cerebrospinal fluid analysis revealed eosinophilic pleocytosis (total nucleated cell count: 12 to 430/μL, 33 to 89% eosinophils). All 6 goats were treated with fenbendazole and anti-inflammatory drugs (NSAIDs ± corticosteroids) and 4 received physical rehabilitation therapy. At discharge or follow-up, all 6 goats were ambulatory and had minimal neurologic deficits. Key clinical message: In goats, cerebrospinal nematodiasis caused by is often a presumptive diagnosis based on neurologic signs, shared habitat with white-tailed deer, eosinophilic pleocytosis, and response to anthelmintic therapy. Presumptive cases in goats have many similarities to confirmed cases in camelids. Further study is indicated to characterize the clinical signs and optimize the diagnosis and treatment of goats infected with .
本回顾性研究描述了疑似脑脊髓线虫病的山羊的临床症状、诊断方法、治疗和结果。根据神经症状、脑脊液分析结果和治疗反应做出疑似诊断。符合纳入标准的山羊有 6 只。脑脊液分析显示嗜酸性粒细胞增多(总核细胞计数:12 至 430/μL,33 至 89%嗜酸性粒细胞)。6 只山羊均用芬苯达唑和抗炎药物(非甾体抗炎药±皮质类固醇)治疗,4 只接受物理康复治疗。出院或随访时,6 只山羊均能行走,仅有轻微的神经缺陷。关键临床信息:在山羊中,由 引起的脑脊髓线虫病通常是基于神经症状、与白尾鹿共同生活、嗜酸性粒细胞增多和驱虫治疗反应做出的疑似诊断。山羊中的疑似病例与骆驼中的确诊病例有许多相似之处。需要进一步研究以描述临床症状并优化感染 的山羊的诊断和治疗。