Dong Xiaopeng, Guo Xuliang, Liu Guangqin, Fan Aiping, Wang Zheng, Zhao Yanjun
School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China.
Chem Commun (Camb). 2017 Mar 30;53(27):3822-3825. doi: 10.1039/c7cc00914c.
The topology of hydrophobic moieties can affect the stability of self-assembled micelles. Curved corannulene and flat perylene were selected as model hydrophobic molecules with poly(ethylene glycol) as the hydrophilic segment. The curvature can enhance the intermolecular π-π interaction, and hence the driving force of micelle formation.
疏水部分的拓扑结构会影响自组装胶束的稳定性。选择弯曲的碗烯和平坦的苝作为模型疏水分子，以聚乙二醇作为亲水链段。曲率可以增强分子间的π-π相互作用，从而增强胶束形成的驱动力。
