Cayuela A, Cayuela L, Rodríguez-Domínguez S, González A, Moniche F
Unidad de Gestión Clínica de Salud Pública, Prevención y Promoción de la Salud, Área de Gestión Sanitaria Sur de Sevilla, Sevilla, España.
Facultad de Medicina, Universidad de Sevilla, Sevilla, España.
Neurologia (Engl Ed). 2019 Jun;34(5):309-317. doi: 10.1016/j.nrl.2016.12.007. Epub 2017 Mar 18.
In recent decades, mortality rates for cerebrovascular diseases (CVD) have decreased significantly in many countries. This study analyses recent tendencies in CVD mortality rates in Andalusia (1980-2014) to identify any changes in previously observed sex and age trends.
CVD mortality and population data were obtained from Spain's National Statistics Institute database. We calculated age-specific and age-standardised mortality rates using the direct method (European standard population). Joinpoint regression analysis was used to estimate the annual percentage change in rates and identify significant changes in mortality trends. We also estimated rate ratios between Andalusia and Spain.
Standardised rates for both males and females showed 3 periods in joinpoint regression analysis: an initial period of significant decline (1980-1997), a period of rate stabilisation (1997-2003), and another period of significant decline (2003-2014).
Between 1997 and 2003, age-standardised rates stabilised in Andalusia but continued to decrease in Spain as a whole. This increased in the gap between CVD mortality rates in Andalusia and Spain for both sexes and most age groups.
近几十年来，许多国家的脑血管疾病（CVD）死亡率显著下降。本研究分析了安达卢西亚地区（1980 - 2014年）CVD死亡率的近期趋势，以确定先前观察到的性别和年龄趋势是否有任何变化。
CVD死亡率和人口数据来自西班牙国家统计局数据库。我们使用直接法（欧洲标准人口）计算了特定年龄和年龄标准化死亡率。采用连接点回归分析来估计死亡率的年度百分比变化，并确定死亡率趋势的显著变化。我们还估计了安达卢西亚与西班牙之间的比率。
在连接点回归分析中，男性和女性的标准化死亡率均显示出三个阶段：最初的显著下降期（1980 - 1997年）、死亡率稳定期（1997 - 2003年）以及另一个显著下降期（2003 - 2014年）。
1997年至2003年期间，安达卢西亚的年龄标准化死亡率趋于稳定，但西班牙整体仍在下降。这使得安达卢西亚与西班牙在男女及大多数年龄组的CVD死亡率差距增大。
