Henriques Ana, Araújo Carla, Viana Marta, Laszczynska Olga, Pereira Marta, Bennett Kathleen, Lunet Nuno, Azevedo Ana
EPIUnit - Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.
EPIUnit - Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal; Department of Cardiology, Centro Hospitalar Trás-os-Montes-e-Alto-Douro, Vila Real, Portugal; Department of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto Medical School, Porto, Portugal.
Rev Port Cardiol. 2017 Apr;36(4):273-281. doi: 10.1016/j.repc.2016.08.011. Epub 2017 Mar 16.
Estimates of the burden of ischemic heart disease (IHD), including geographic differences, should support health policy decisions. We set out to estimate the burden of IHD in mainland Portugal in 2013 by calculating disability-adjusted life years (DALYs) and to compare this burden between five regions.
Years of life lost (YLLs) were calculated by multiplying the number of IHD deaths in 2013 (Statistics Portugal) by the life expectancy at the age at which death occurred. Years lived with disability (YLDs) were computed as the number of cases of acute coronary syndrome, stable angina and ischemic heart failure multiplied by an average disability weight. Crude and age-standardized DALYs (direct method, Standard European Population) were calculated for mainland Portugal and for the Northern, Central, Lisbon, Alentejo and Algarve regions.
In 2013, 95413 DALYs were lost in mainland Portugal due to IHD. YLLs accounted for 88.3% of the disease burden. Age-standardized DALY rates per 1000 population were higher in men than in women, across the entire country (8.9 in men; 3.4 in women) and within each region, ranging from 7.3 in the Northern and Central regions to 11.8 in the Algarve in men, and from 2.6 in the Northern region to 4.6 in Lisbon in women.
Nearly 100000 DALYs were lost to IHD in Portugal, mostly through early mortality. This study enables accurate comparisons with other countries and between regions; however, it highlights the need for population-based studies to obtain specific data on morbidity.
对缺血性心脏病(IHD)负担的评估,包括地理差异,应能为卫生政策决策提供支持。我们旨在通过计算伤残调整生命年(DALYs)来估算2013年葡萄牙大陆地区缺血性心脏病的负担,并比较五个地区之间的这一负担情况。
通过将2013年IHD死亡人数(葡萄牙统计局数据)乘以死亡年龄的预期寿命来计算生命损失年数(YLLs)。失能生存年数(YLDs)通过急性冠脉综合征、稳定型心绞痛和缺血性心力衰竭病例数乘以平均失能权重来计算。计算了葡萄牙大陆地区以及北部、中部、里斯本、阿连特茹和阿尔加维地区的粗DALYs和年龄标准化DALYs(直接法,标准欧洲人口)。
2013年,葡萄牙大陆地区因IHD损失了95413个DALYs。YLLs占疾病负担的88.3%。全国范围内以及各地区,每1000人口的年龄标准化DALY率男性均高于女性(男性为8.9;女性为3.4),男性从北部和中部地区的7.3到阿尔加维地区的11.8不等,女性从北部地区的2.6到里斯本地区的4.6不等。
葡萄牙因IHD损失了近10万个DALYs,主要是由于过早死亡。本研究能够与其他国家以及各地区进行准确比较;然而,它强调了开展基于人群的研究以获取发病率具体数据的必要性。