Henderson Robert A, Austin Matthew S
Division of Adult Reconstruction, Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University, Philadelphia, Pennsylvania.
J Arthroplasty. 2017 Jul;32(7):2056-2059. doi: 10.1016/j.arth.2017.02.023. Epub 2017 Feb 23.
Despite the tremendous and long-standing success of total hip arthroplasty and total knee arthroplasty as treatments for end-stage arthritis, periprosthetic joint infection (PJI) remains a rare but feared complication of these procedures.
This review highlights some of the difficulties inherent to studying PJI. These include the difficulty in powering studies to capture this relatively uncommon complication, as well as the heterogeneity in clinical presentation and manifestations associated with the diagnosis and treatment of PJI.
We suggest an algorithm for moving forward with new research in an attempt to answer the challenging questions facing the arthroplasty community regarding PJI.
尽管全髋关节置换术和全膝关节置换术作为终末期关节炎的治疗方法取得了巨大且长期的成功，但假体周围关节感染（PJI）仍然是这些手术中一种罕见但令人担忧的并发症。
本综述强调了研究PJI所固有的一些困难。这些困难包括难以开展有足够效力的研究来捕捉这种相对不常见的并发症，以及PJI诊断和治疗相关临床表现和表现形式的异质性。
我们提出一种算法，以推进新的研究，试图回答关节置换领域在PJI方面面临的具有挑战性的问题。
