Department of Chemistry, Humboldt-Universität zu Berlin, Brook-Taylor-Strasse 2, 12489, Berlin, Germany.
Angew Chem Int Ed Engl. 2017 Apr 3;56(15):4300-4304. doi: 10.1002/anie.201612417. Epub 2017 Mar 20.
The activation of SF at [Pt(PR ) ] R=Cy, iPr complexes in the presence of PR led selectively and in an unprecedented reaction route to the generation of the SF complexes trans-[Pt(F)(SF )(PR ) ]. These can also be synthesized from SF and the SF derivative trans-[Pt(F)(SF )(PCy ) ][BF ] was characterized by X-ray crystallography. trans-[Pt(F)(SF )(PR ) ] complexes are useful tools for deoxyfluorination reactions and novel fluorido complexes bearing a SOF ligand are formed. Based on these studies a process for the deoxyfluorination of ketones was developed with SF as fluorinating agent.
在 PR 的存在下，[Pt(PR ) ] R=Cy，iPr 配合物中 SF 的活化选择性地且以前所未有的反应途径生成 SF 配合物反式-[Pt(F)(SF )(PR ) ]。这些也可以从 SF 和 SF 衍生物反式-[Pt(F)(SF )(PCy ) ][BF ]合成得到，并用 X 射线晶体学进行了表征。反式-[Pt(F)(SF )(PR ) ]配合物是脱氟反应的有用工具，并且形成了带有 SOF 配体的新型氟化物配合物。基于这些研究，开发了一种以 SF 为氟源的酮脱氟工艺。
