Manskikh V N
Lomonosov Moscow State University, Faculty of Bioengineering and Bioinformatics, Moscow, 119991, Russia.
Biochemistry (Mosc). 2017 Jan;82(1):81-85. doi: 10.1134/S0006297917010096.
Arguments supporting the "bad luck" hypothesis presented by C. Tomasetti and B. Vogelstein ((2015) Science, 347, 78-81) and A. V. Lichtenstein ((2017) Biochemistry (Moscow), 82, 75-80) are critically discussed. Those arguments are not sufficient for recognition of the "bad luck" hypothesis and the leading role of internal factors in spontaneous tumor development.
对C. 托马塞蒂和B. 沃格斯坦（（2015年）《科学》，347卷，78 - 81页）以及A. V. 利希滕斯坦（（2017年）《生物化学（莫斯科）》，82卷，75 - 80页）提出的“坏运气”假说的支持论据进行了批判性讨论。这些论据不足以认可“坏运气”假说以及内部因素在自发肿瘤发生中的主导作用。
