Wang Yujie, Xue Jian, Jin Hongyu, Ma Shuangcheng
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College.
National Institutes for Food and Drug Control.
Chem Pharm Bull (Tokyo). 2017 May 1;65(5):492-497. doi: 10.1248/cpb.c16-01015. Epub 2017 Mar 18.
The dissipation of flonicamid in Honeysuckle and transfer pattern from Honeysuckle to its tea infusion were investigated. Flonicamid was applied on Honeysuckle crop at two dosages, 60 g of active gradient per hectare (g a.i. hm) and 180 g a.i. hm (recommended and triple the recommended) in Fenqiu, Henan Province in 2015 and 2016. Gas Chromatography-Electron Capture Detector (GC-ECD) detection methods were developed for the analysis of flonicamid residues in honeysuckles and its infusion. The recoveries in both honeysuckles and its infusion ranged from 81.5 to 101.7% with relative standard deviations (RSDs) of 3.2-9.1%. The dissipations of flonicamid in Honeysuckle were found to follow the first order kinetics with half-life ranging between 2.8 and 3.2 d. After recommended dose pesticide application, contents of flonicamid residues were lower than theoretical maximum residue limit (tMRL). Flonicamid residues can easily transfer from Honeysuckle to its tea infusion and transfer rates of flonicamid decrease with the brewing temperature reduction or the brewing times increase. These results are helpful to establish maximum residue limit and develop guidance on the appropriate and secure use of flonicamid in Honeysuckle.
研究了氟啶虫酰胺在金银花中的消解情况及其从金银花到茶汤的转移规律。2015年和2016年在河南封丘，以每公顷60克有效成分（g a.i. hm）和180克有效成分（g a.i. hm）（推荐剂量和推荐剂量的三倍）两种剂量在金银花作物上施用氟啶虫酰胺。建立了气相色谱 - 电子捕获检测器（GC - ECD）检测方法，用于分析金银花及其茶汤中的氟啶虫酰胺残留。金银花及其茶汤中的回收率在81.5%至101.7%之间，相对标准偏差（RSD）为3.2 - 9.1%。发现氟啶虫酰胺在金银花中的消解符合一级动力学，半衰期在2.8至3.2天之间。按照推荐剂量施用农药后，氟啶虫酰胺残留量低于理论最大残留限量（tMRL）。氟啶虫酰胺残留可轻易从金银花转移到其茶汤中，且氟啶虫酰胺的转移率随冲泡温度降低或冲泡次数增加而降低。这些结果有助于制定氟啶虫酰胺在金银花中的最大残留限量，并为其在金银花中的合理安全使用提供指导。
