Sarfaraz Moaziz, Syeda Rana Hasan
Emergency Department, Fujairah Hospital.
Emergency Department, Masafi Hospital.
Drug Discov Ther. 2017 May 30;11(2):115-117. doi: 10.5582/ddt.2016.01082. Epub 2017 Mar 19.
Levetiracetam and topiramate are newer anticonvulsants, which is why international data on overdoses of these drugs are lacking. Only a few mild adverse reactions have been noted. These anticonvulsants have been the drug of choice for neurologists. Despite their wide usage, there is a dearth of literature on symptoms and signs of their toxicity. Presented here is the case of a 21-year-old female who overdosed twice on levetiracetam and topiramate. The woman was admitted and discharged after the first overdose. Ten days later, she took multiple tablets of both drugs and was seen again. Amazingly, the woman went home after the incident with no complications at all.
左乙拉西坦和托吡酯是较新的抗惊厥药物，这就是为何缺乏关于这些药物过量的国际数据。仅记录到少数轻微不良反应。这些抗惊厥药物一直是神经科医生的首选药物。尽管它们被广泛使用，但关于其毒性症状和体征的文献却很匮乏。本文介绍了一名21岁女性两次过量服用左乙拉西坦和托吡酯的病例。该女性在首次过量服药后入院并出院。十天后，她又服用了两种药物的多片药片，随后再次就诊。令人惊讶的是，该女性在事件发生后回家，没有出现任何并发症。
