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嗜铬细胞瘤所致可逆性儿茶酚胺诱导性心肌病急性期患者心肌活检标本的组织学特征

The Histological Features of a Myocardial Biopsy Specimen in a Patient in the Acute Phase of Reversible Catecholamine-induced Cardiomyopathy due to Pheochromocytoma.

作者信息

Miura Miyuki, Kawano Hiroaki, Yoshida Takeo, Yamagata Yuki, Nakata Tomoo, Koga Seiji, Ikeda Satoshi, Kageyama Kan, Abe Kuniko, Maemura Koji

机构信息

Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.

出版信息

Intern Med. 2017;56(6):665-671. doi: 10.2169/internalmedicine.56.7454. Epub 2017 Mar 17.

DOI:10.2169/internalmedicine.56.7454
PMID:28321067
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5410477/
Abstract

A 63-year-old Japanese woman with an adrenal tumor was transferred to our hospital due to cardiogenic shock. Right and left ventriculography showed severe hypokinesis of the middle segment and the apex in both ventricles, and an endomyocardial biopsy demonstrated a small number of necrotic myocytes and cellular infiltration. She was diagnosed with pheochromocytoma and quickly recovered after treatment with an α-blocker. The functional disability of both the right and left ventricles with less myocardial damage due to an excessive level of catecholamine seemed to be related to the early recovery the present patient with catecholamine-induced cardiomyopathy due to pheochromocytoma.

摘要

一名63岁患有肾上腺肿瘤的日本女性因心源性休克被转至我院。左右心室造影显示双心室中间段和心尖严重运动减弱,心内膜活检显示少量坏死心肌细胞和细胞浸润。她被诊断为嗜铬细胞瘤,经α受体阻滞剂治疗后迅速康复。由于儿茶酚胺水平过高导致的左右心室功能障碍且心肌损伤较轻,这似乎与该例因嗜铬细胞瘤导致儿茶酚胺诱导性心肌病的患者早期康复有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5828/5410477/be3697003409/1349-7235-56-0665-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5828/5410477/586c3d90a2d3/1349-7235-56-0665-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5828/5410477/4a71ada1f756/1349-7235-56-0665-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5828/5410477/8743f4e09546/1349-7235-56-0665-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5828/5410477/151415db5437/1349-7235-56-0665-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5828/5410477/be3697003409/1349-7235-56-0665-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5828/5410477/586c3d90a2d3/1349-7235-56-0665-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5828/5410477/4a71ada1f756/1349-7235-56-0665-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5828/5410477/8743f4e09546/1349-7235-56-0665-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5828/5410477/151415db5437/1349-7235-56-0665-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5828/5410477/be3697003409/1349-7235-56-0665-g005.jpg

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Endomyocardial biopsy in a patient with hemorrhagic pheochromocytoma presenting as inverted Takotsubo cardiomyopathy.表现为倒Tako-Tsubo心肌病的出血性嗜铬细胞瘤患者的心内膜心肌活检
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Prevalence and patterns of left ventricular dysfunction in patients with pheochromocytoma.
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