Kennedy M J, Shelley R K, Daly P A
Department of Haematology/Oncology, St. James's Hospital, Dublin, Ireland.
Eur J Respir Dis. 1987 Nov;71(5):450-4.
The syndrome of inappropriate anti-diuretic hormone secretion (SIADH) is a feature of approximately 7% of cases of small cell lung cancer (SCLC). The elaboration of peptide hormones by this tumour is well recognised and cerebral oedema resulting from inappropriate ADH secretion may be a life-threatening complication of this illness, requiring prompt intervention. We report a patient with SCLC who presented with SIADH which worsened abruptly each time he was treated with trifluoperazine for a co-existing psychosis.
抗利尿激素分泌不当综合征（SIADH）是约7%的小细胞肺癌（SCLC）病例的一个特征。这种肿瘤分泌肽类激素已得到充分认识，抗利尿激素分泌不当导致的脑水肿可能是这种疾病的一种危及生命的并发症，需要及时干预。我们报告一名患有小细胞肺癌的患者，他出现了抗利尿激素分泌不当综合征，每次因并存的精神病用三氟拉嗪治疗时病情都会突然恶化。
