Gifu Pharmaceutical University 1-25-4, Daigaku-nishi, Gifu 501-1196, Japan.
Org Lett. 2017 Apr 7;19(7):1610-1613. doi: 10.1021/acs.orglett.7b00428. Epub 2017 Mar 21.
A metal-free photo-oxidative intermolecular C-H/C-H coupling reaction of thiophenes is demonstrated with carbonyls using a catalytic amount of molecular iodine. In this system, molecular oxygen in the air acted as a terminal oxidant to regenerate molecular iodine. A mechanistic study was also performed.
本文展示了一种无需金属的光氧化分子间 C-H/C-H 交叉偶联反应，该反应使用催化量的分子碘，以硫酚和羰基化合物作为底物。在此体系中，空气中的分子氧作为末端氧化剂来再生分子碘。同时还进行了机理研究。
