Ecklund-Flores Lisa, Myers Michael M, Monk Catherine, Perez Albany, Odendaal Hein J, Fifer William P
Department of Psychology, Mercy College, Dobbs Ferry, New York.
Division of Developmental Neuroscience, New York State Psychiatric Institute, New York, New York.
Dev Psychobiol. 2017 Apr;59(3):314-323. doi: 10.1002/dev.21496.
Previous research of maternal depression during pregnancy suggests an association with low birth weight in newborns. Review of these studies reveals predominant comorbidity with premature birth. This current study examines antenatal depression and birth weight in term, medically low-risk pregnancies. Maternal physiological and demographic measures were collected as well. In total, 227 pregnant women were recruited to participate in four experimental protocols at Columbia University Medical Center. Results indicate that depressed pregnant women who carry to term had significantly higher heart rates, lower heart rate variability, and gave birth to heavier babies than those of pregnant women who were not depressed. Low income participants had significantly higher levels of depression, as well as significantly higher heart rates and lower heart rate variability, than those in higher income groups. In full-term infants, maternal prenatal depression appears to promote higher birth weight, with elevated maternal heart rate as a likely mediating mechanism.
先前关于孕期母亲抑郁的研究表明，这与新生儿低出生体重有关。对这些研究的综述显示，早产是主要的合并症。本研究调查足月、医学低风险妊娠中的产前抑郁与出生体重。同时还收集了母亲的生理和人口统计学指标。共有227名孕妇被招募到哥伦比亚大学医学中心参与四项实验方案。结果表明，足月分娩的抑郁孕妇心率显著更高、心率变异性更低，且所生婴儿比未抑郁的孕妇所生婴儿更重。低收入参与者的抑郁水平显著高于高收入组，心率也显著更高，心率变异性更低。在足月儿中，母亲产前抑郁似乎会促使出生体重增加，母亲心率升高可能是一种中介机制。
