Gala Raj J, Russo Glenn S, Whang Peter G
Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, 47 College Street, New Haven, CT, 06510, USA.
Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, PO Box 208071, New Haven, CT, 06520-8071, USA.
Curr Rev Musculoskelet Med. 2017 Jun;10(2):182-188. doi: 10.1007/s12178-017-9413-8.
Lumbar spinal stenosis has historically been treated with open decompressive surgery which is associated with significant morbidity and may give rise to various complications. Interspinous spacers (ISS) have been developed as a less invasive strategy which may serve to avoid many of these risks. The two current spacers that are FDA approved and commercially available are the Coflex and Superion devices. The goal is to review these two implants, their indications, and patient selection.
The Coflex device has been shown to be analogous to decompression and fusion when treating moderate spinal stenosis. It provides dynamic stability after a decompression is performed, without the rigidity of pedicle-screw instrumentation. Recent results show improved outcomes in Coflex patients at 3 years of follow-up, as compared to decompression and fusion. The Superion implant is placed percutaneously in the interspinous space with minimal disruption of spinal anatomy. When compared to the X-Stop device (which is no longer available), the Superion implant shows improved outcomes at 3 years of follow-up. ISS are lesser invasive options as compared to formal decompression and fusion for the treatment of lumbar spinal stenosis.
腰椎管狭窄症历来采用开放减压手术治疗,该手术具有较高的发病率,并可能引发各种并发症。棘突间撑开器(ISS)已被开发为一种侵入性较小的策略,有望避免许多此类风险。目前两种获得美国食品药品监督管理局(FDA)批准并可商业使用的撑开器是Coflex和Superion装置。目的是对这两种植入物、其适应症和患者选择进行综述。
Coflex装置在治疗中度椎管狭窄时已被证明类似于减压和融合手术。在进行减压后,它能提供动态稳定性,而没有椎弓根螺钉器械的僵硬性。最近的结果显示,与减压和融合手术相比,Coflex患者在3年随访时的结果有所改善。Superion植入物通过经皮方式放置在棘突间间隙,对脊柱解剖结构的破坏最小。与X-Stop装置(现已不再可用)相比,Superion植入物在3年随访时显示出更好的结果。与正式的减压和融合手术相比,ISS是治疗腰椎管狭窄症侵入性较小的选择。