Kouchaki Z, Butlin M, Qasem A, Avolio A P
Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:2941-2944. doi: 10.1109/EMBC.2016.7591346.
Systolic blood pressure variability (BPV) is associated with cardiovascular events. As the beat-to-beat variation of blood pressure is due to interaction of several cardiovascular control systems operating with different response times, assessment of BPV by spectral analysis using the continuous measurement of arterial pressure in the finger is used to differentiate the contribution of these systems in regulating blood pressure. However, as baroreceptors are centrally located, this study considered applying a continuous aortic pressure signal estimated noninvasively from finger pressure for assessment of systolic BPV by a time-frequency method using Short Time Fourier Transform (STFT). The average ratio of low frequency and high frequency power band (LF/HF) was computed by time-frequency decomposition of peripheral systolic pressure (pSBP) and derived central aortic systolic blood pressure (cSBP) in 30 healthy subjects (25-62 years) as a marker of balance between cardiovascular control systems contributing in low and high frequency blood pressure variability. The results showed that the BPV assessed from finger pressure (pBPV) overestimated the BPV values compared to that assessed from central aortic pressure (cBPV) for identical cardiac cycles (P<;0.001), with the overestimation being greater at higher power.
收缩压变异性（BPV）与心血管事件相关。由于血压的逐搏变化是由几个具有不同响应时间的心血管控制系统相互作用所致，通过对手指动脉压进行连续测量，采用频谱分析评估BPV，以区分这些系统在调节血压中的作用。然而，由于压力感受器位于中枢，本研究考虑应用从手指压力无创估计的连续主动脉压力信号，通过使用短时傅里叶变换（STFT）的时频方法评估收缩压BPV。对30名健康受试者（25 - 62岁）的外周收缩压（pSBP）和推导得出的中心主动脉收缩压（cSBP）进行时频分解，计算低频与高频功率带的平均比值（LF/HF），作为对低频和高频血压变异性有贡献的心血管控制系统之间平衡的标志物。结果显示，在相同心动周期中，与从中心主动脉压力评估的BPV（cBPV）相比，从手指压力评估的BPV（pBPV）高估了BPV值（P<0.001），且在较高功率时高估更为明显。
